Adam Rolt

Affiliations: 
University of Oxford, Oxford, United Kingdom 
Area:
Drug discovery
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Parents

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T. Jake Liang grad student (Neurotree)
Andrew Stachulski grad student Liverpool
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Publications

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Rolt A, Talley DC, Park SB, et al. (2021) Discovery and Optimization of a 4-Aminopiperidine Scaffold for Inhibition of Hepatitis C Virus Assembly. Journal of Medicinal Chemistry
Ma CD, Imamura M, Talley DC, et al. (2020) Fluoxazolevir inhibits hepatitis C virus infection in humanized chimeric mice by blocking viral membrane fusion. Nature Microbiology
Hu Z, Rolt A, Hu X, et al. (2020) Chlorcyclizine Inhibits Viral Fusion of Hepatitis C Virus Entry by Directly Targeting HCV Envelope Glycoprotein 1. Cell Chemical Biology
Rolt A, O'Neill PM, Liang TJ, et al. (2019) Synthesis of MeBmt and related derivatives syn-selective ATH-DKR. Rsc Advances. 9: 40336-40339
Rolt A, Le D, Hu Z, et al. (2018) Preclinical Pharmacological Development of Chlorcyclizine Derivatives for the Treatment of Hepatitis C Virus Infection. The Journal of Infectious Diseases
He S, Xiao J, Dulcey AE, et al. (2015) Discovery, Optimization, and Characterization of Novel Chlorcyclizine Derivatives for the Treatment of Hepatitis C Virus Infection. Journal of Medicinal Chemistry
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