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Yimon Aye, Ph.D.

Affiliations:	2012-2018		Cornell University, Ithaca, NY, United States
	2018-		École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland

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Parents

David A. Evans	grad student	2009	Harvard
(I. Asymmetric catalysis )
JoAnne Stubbe	post-doc	2009-2012	MIT

Children

Souradyuti Ghosh	post-doc	2015-2016	Cornell
Xiaopeng Yin	post-doc	2017-2018	Cornell
Amogh Kulkarni	post-doc	2020-2021	Swiss Federal Institute of Technology (EPFL)

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Publications

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Huang KT, Ly P, Poganik JR, et al. (2023) Monitoring On-Target Signaling Responses in Larval Zebrafish - Z-REX Unmasks Precise Mechanisms of Electrophilic Drugs and Metabolites. Journal of Visualized Experiments : Jove
Long MJC, Aye Y. (2022) Keap 1: the new Janus word on the block. Bioorganic & Medicinal Chemistry Letters. 128766
Zhao Y, Miranda Herrera PA, Chang D, et al. (2022) Function-guided proximity mapping unveils electrophilic-metabolite sensing by proteins not present in their canonical locales. Proceedings of the National Academy of Sciences of the United States of America. 119
Long MJC, Kulkarni A, Aye Y. (2021) Can Precision Electrophile Signaling Make a Meaningful and Lasting Impression in Drug Design? Chembiochem : a European Journal of Chemical Biology
Long MJC, Rogg C, Aye Y. (2020) An Oculus to Profile and Probe Target Engagement In Vivo: How T-REX Was Born and Its Evolution into G-REX. Accounts of Chemical Research
Aye Y. (2020) Where Electrophile Signaling and Covalent Ligand-Target Mining Converge. Chimia. 74: 659-666
Liu X, Long MJC, Hopkins BD, et al. (2020) Precision Targeting of -Null Triple-Negative Breast Tumors Guided by Electrophilic Metabolite Sensing. Acs Central Science. 6: 892-902
Poganik JR, Aye Y. (2020) Electrophile Signaling and Emerging Immuno- and Neuro-modulatory Electrophilic Pharmaceuticals. Frontiers in Aging Neuroscience. 12: 1
Long MJC, Urul DA, Aye Y. (2020) REX technologies for profiling and decoding the electrophile signaling axes mediated by Rosetta Stone proteins. Methods in Enzymology. 633: 203-230
Long MJC, Zhao Y, Aye Y. (2019) Clofarabine Commandeers the RNR-α-ZRANB3 Nuclear Signaling Axis. Cell Chemical Biology

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