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Samuel Ellis Holtzen, PhD

Affiliations: 
California Institute of Technology, Pasadena, CA 
Area:
biosensors, imaging
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"Samuel Holtzen"
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Parents

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Amanda M. Stockton research assistant 2015-2018 Georgia Tech
Adam M. Guss research assistant 2018-2019 (Microtree)
Amy E. Palmer grad student 2020-2024 CU Boulder
David Van Valen post-doc 2024- Caltech (Physics Tree)
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Publications

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Woyciehowsky M, Larson P, Stephan AR, et al. (2025) Systematic characterization of zinc in a series of breast cancer cell lines reveals significant changes in zinc homeostasis. Biorxiv : the Preprint Server For Biology
Tan G, LeCates CN, Simpson A, et al. (2025) Amplicon Sequencing Reveals Diversity in Spatially Separated Microbial Communities in the Icelandic Mars Analog Environment Mælifellssandur. Astrobiology
Ocampo D, Damon LJ, Sanford L, et al. (2024) Cellular zinc status alters chromatin accessibility and binding of p53 to DNA. Life Science Alliance. 7
Holtzen SE, Rakshit A, Palmer AE. (2024) Protocol for measuring labile cytosolic Zn using an in situ calibration of a genetically encoded FRET sensor. Star Protocols. 5: 103130
Holtzen SE, Rakshit A, Palmer AE. (2024) Protocol for measuring cell cycle Zn dynamics using a FRET-based biosensor. Star Protocols. 5: 103122
Holtzen SE, Navid E, Kainov JD, et al. (2024) Transient Zn deficiency induces replication stress and compromises daughter cell proliferation. Proceedings of the National Academy of Sciences of the United States of America. 121: e2321216121
Holtzen SE, Navid E, Kainov JD, et al. (2023) Transient Zn deficiency induces replication stress and compromises daughter cell proliferation. Biorxiv : the Preprint Server For Biology
Rakshit A, Holtzen SE, Lo MN, et al. (2023) Human cells experience a Zn pulse in early G1. Cell Reports. 42: 112656
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