Hans-Dieter Höltje

Pharmacy Heinrich Heine University Düsseldorf, Düsseldorf, Nordrhein-Westfalen, Germany 
Pharmaceutical Chemistry
"Hans-Dieter Höltje"
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Hillmann P, Ko GY, Spinrath A, et al. (2009) Key determinants of nucleotide-activated G protein-coupled P2Y2 receptor function revealed by chemical and pharmacological experiments, mutagenesis and homology modeling Journal of Medicinal Chemistry. 52: 2762-2775
Thielmann Y, Mohrlüder J, Koenig BW, et al. (2008) An indole-binding site is a major determinant of the ligand specificity of the GABA type A receptor-associated protein GABARAP Chembiochem. 9: 1767-1775
Schlegel B, Laggner C, Meier R, et al. (2007) Generation of a homology model of the human histamine H3 receptor for ligand docking and pharmacophore-based screening Journal of Computer-Aided Molecular Design. 21: 437-453
Schlegel B, Sippl W, Höltje HD. (2005) Molecular dynamics simulations of bovine rhodopsin: Influence of protonation states and different membrane-mimicking environments Journal of Molecular Modeling. 12: 49-64
Schlegel B, Stark H, Sippl W, et al. (2005) Model of a specific human histamine H3 receptor (hH 3R) binding pocket suitable for virtual drug design Inflammation Research. 54: S50-S51
Jöhren K, Höltje HD. (2005) Different environments for a realistic simulation of GPCRs-application to the M2 muscarinic receptor Archiv Der Pharmazie. 338: 260-267
Terzioglu N, Höltje HD. (2005) Receptor-based 3D QSAR analysis of serotonin 5-HT1D receptor agonists Collection of Czechoslovak Chemical Communications. 70: 1482-1492
Bröer BM, Gurrath M, Höltje HD. (2003) Molecular modelling studies on the ORL1-receptor and ORL1-agonists Journal of Computer-Aided Molecular Design. 17: 739-754
Hammer S, Spika I, Sippl W, et al. (2003) Glucocorticoid receptor interactions with glucocorticoids: Evaluation by molecular modeling and functional analysis of glucocorticoid receptor mutants Steroids. 68: 329-339
Jöhren K, Höltje HD. (2002) A model of the human M2 muscarinic acetylcholine receptor Journal of Computer-Aided Molecular Design. 16: 795-801
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