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George P. Smith

1975- Biological Sciences University of Missouri - Columbia, Columbia, MO, United States 
Molecular imaging of cancer through phage display
"George P. Smith"
The Nobel Prize in Chemistry 2018 was divided, one half awarded to Frances H. Arnold "for the directed evolution of enzymes", the other half jointly to George P. Smith and Sir Gregory P. Winter "for the phage display of peptides and antibodies."

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Edgar Haber grad student 1970 Harvard
 (The variation and adaptive expression of antibodies.)
Oliver Smithies post-doc 1970-1975 UW Madison
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Newton-Northup JR, Dickerson MT, Kumar SR, et al. (2014) In vivo bacteriophage peptide display to tailor pharmacokinetics of biological nanoparticles. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 16: 854-64
Larimer BM, Thomas WD, Smith GP, et al. (2014) Affinity maturation of an ERBB2-targeted SPECT imaging peptide by in vivo phage display. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 16: 449-58
Thomas WD, Smith GP. (2010) The case for trypsin release of affinity-selected phages. Biotechniques. 49: 651-4
Thomas WD, Golomb M, Smith GP. (2010) Corruption of phage display libraries by target-unrelated clones: diagnosis and countermeasures. Analytical Biochemistry. 407: 237-40
van Houten NE, Henry KA, Smith GP, et al. (2010) Engineering filamentous phage carriers to improve focusing of antibody responses against peptides. Vaccine. 28: 2174-85
Jin X, Newton JR, Montgomery-Smith S, et al. (2009) A generalized kinetic model for amine modification of proteins with application to phage display. Biotechniques. 46: 175-82
Mizejewski G, Smith G, Butterstein G. (2005) Review and proposed action of alpha-fetoprotein growth inhibitory peptides as estrogen and cytoskeleton-associated factors. Cell Biology International. 28: 913-33
Smith GP, Fernández AM. (2004) Effect of DNA copy number on genetic stability of phage-displayed peptides. Biotechniques. 36: 610-4, 616, 618
Petrenko VA, Smith GP, Mazooji MM, et al. (2002) Alpha-helically constrained phage display library. Protein Engineering. 15: 943-50
Matthews LJ, Davis R, Smith GP. (2002) Immunogenically fit subunit vaccine components via epitope discovery from natural peptide libraries. Journal of Immunology (Baltimore, Md. : 1950). 169: 837-46
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