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Stephen F Betz, PhD

Affiliations: 
Crinetics Pharmaceuticals 
Area:
Endocrinology, Pharmacology, Biology, GPCRs, Drug Discovery, Drug Development
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"Stephen Betz"
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Parents

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Harold  B. White, III research assistant 1985-1987 University of Delaware
Gary J. Pielak grad student 1988-1993 UNC Chapel Hill
William F. DeGrado post-doc 1993-1996 DuPont Merck Pharmaceuticals Company

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BETA: Related publications

Publications

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BETZ SF, BRYSON JW, PASSADOR MC, et al. (2010) ChemInform Abstract: Expression of de novo Designed α-Helical Bundles Cheminform. 27: no-no
Walsh ST, Sukharev VI, Betz SF, et al. (2001) Hydrophobic core malleability of a de novo designed three-helix bundle protein. Journal of Molecular Biology. 305: 361-73
Liu Z, Sun C, Olejniczak ET, et al. (2000) Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain. Nature. 408: 1004-8
Betz SF, Liebman PA, DeGrado WF. (1997) De novo design of native proteins: characterization of proteins intended to fold into antiparallel, rop-like, four-helix bundles. Biochemistry. 36: 2450-8
Betz SF, Raleigh DP, DeGrado WF, et al. (1996) Crystallization of a designed peptide from a molten globule ensemble Folding and Design. 1: 57-64
Betz SF, Bryson JW, Passador MC, et al. (1996) Expression of de novo designed alpha-helical bundles. Acta Chemica Scandinavica (Copenhagen, Denmark : 1989). 50: 688-96
Betz SF, Marmorino JL, Saunders AJ, et al. (1996) Unusual effects of an engineered disulfide on global and local protein stability. Biochemistry. 35: 7422-8
Betz SF, DeGrado WF. (1996) Controlling topology and native-like behavior of de novo-designed peptides: design and characterization of antiparallel four-stranded coiled coils. Biochemistry. 35: 6955-62
Betz SF, Bryson JW, DeGrado WF. (1995) Native-like and structurally characterized designed alpha-helical bundles. Current Opinion in Structural Biology. 5: 457-63
Pielak GJ, Auld DS, Beasley JR, et al. (1995) Protein thermal denaturation, side-chain models, and evolution: amino acid substitutions at a conserved helix-helix interface. Biochemistry. 34: 3268-76
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