carlo melchiorre

Department of Pharmaceutical Sciences School of Pharmacy, Chapel Hill, NC, United States 
"carlo melchiorre"
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Rosini M, Simoni E, Minarini A, et al. (2014) Multi-target design strategies in the context of Alzheimer's disease: acetylcholinesterase inhibition and NMDA receptor antagonism as the driving forces. Neurochemical Research. 39: 1914-23
Rosini M, Simoni E, Milelli A, et al. (2014) Oxidative stress in Alzheimer's disease: are we connecting the dots? Journal of Medicinal Chemistry. 57: 2821-31
Simoni E, Daniele S, Bottegoni G, et al. (2012) Combining galantamine and memantine in multitargeted, new chemical entities potentially useful in Alzheimer's disease. Journal of Medicinal Chemistry. 55: 9708-21
Bolognesi ML, Chiriano G, Bartolini M, et al. (2011) Synthesis of monomeric derivatives to probe memoquin's bivalent interactions. Journal of Medicinal Chemistry. 54: 8299-304
Bolognesi ML, Simoni E, Rosini M, et al. (2011) Multitarget-directed ligands: innovative chemical probes and therapeutic tools against Alzheimer's disease. Current Topics in Medicinal Chemistry. 11: 2797-806
Rosini M, Simoni E, Bartolini M, et al. (2011) Exploiting the lipoic acid structure in the search for novel multitarget ligands against Alzheimer's disease European Journal of Medicinal Chemistry. 46: 5435-5442
Bolognesi ML, Bartolini M, Tarozzi A, et al. (2011) Multitargeted drugs discovery: Balancing anti-amyloid and anticholinesterase capacity in a single chemical entity Bioorganic and Medicinal Chemistry Letters. 21: 2655-2658
Sagratini G, Angeli P, Buccioni M, et al. (2010) Synthesis and α1-adrenoceptor antagonist activity of tamsulosin analogues. European Journal of Medicinal Chemistry. 45: 5800-7
Simoni E, Bergamini C, Fato R, et al. (2010) Polyamine conjugation of curcumin analogues toward the discovery of mitochondria-directed neuroprotective agents Journal of Medicinal Chemistry. 53: 7264-7268
Bolognesi ML, Bartolini M, Mancini F, et al. (2010) Bis(7)-tacrine derivatives as multitarget-directed ligands: Focus on anticholinesterase and antiamyloid activities. Chemmedchem. 5: 1215-20
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