Jakob Franke

Leibniz Universität Hannover 
"Jakob Franke"
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Trottmann F, Ishida K, Franke J, et al. (2020) Sulfonium Acids Loaded onto an Unusual Thiotemplate Assembly Line Construct the Cyclopropanol Warhead of a Burkholderia Virulence Factor. Angewandte Chemie (International Ed. in English)
Trottmann F, Franke J, Richter I, et al. (2019) A Cyclopropanol Warhead in Malleicyprol Confers Virulence of Human- and Animal-Pathogenic Burkholderia Species. Angewandte Chemie (International Ed. in English)
Trottmann F, Franke J, Ishida K, et al. (2018) A Pair of Bacterial Siderophores Releases and Traps an Intercellular Signal Molecule: An Unusual Case of Natural Nitrone Bioconjugation. Angewandte Chemie (International Ed. in English)
Dang TT, Franke J, Carqueijeiro IST, et al. (2018) Sarpagan bridge enzyme has substrate-controlled cyclization and aromatization modes. Nature Chemical Biology
Caputi L, Franke J, Farrow SC, et al. (2018) Missing enzymes in the biosynthesis of the anticancer drug vinblastine in Madagascar periwinkle. Science (New York, N.Y.)
Tatsis EC, Carqueijeiro I, Dugé de Bernonville T, et al. (2017) A three enzyme system to generate the Strychnos alkaloid scaffold from a central biosynthetic intermediate. Nature Communications. 8: 316
Dang TT, Franke J, Tatsis EC, et al. (2017) Dual catalytic activity of a cytochrome P450 controls bifurcation at a metabolic branch point of alkaloid biosynthesis in Rauwolfia serpentina. Angewandte Chemie (International Ed. in English)
Franke J, Hertweck C. (2016) Biomimetic Thioesters as Probes for Enzymatic Assembly Lines: Synthesis, Applications, and Challenges. Cell Chemical Biology
Franke J, Ishida K, Hertweck C. (2015) Plasticity of the malleobactin pathway and its impact on siderophore action in human pathogenic bacteria. Chemistry (Weinheim An Der Bergstrasse, Germany). 21: 8010-4
Baunach M, Franke J, Hertweck C. (2015) Terpenoid biosynthesis off the beaten track: unconventional cyclases and their impact on biomimetic synthesis. Angewandte Chemie (International Ed. in English). 54: 2604-26
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