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Andrew Buller

Affiliations: 
2017- Chemistry University of Wisconsin, Madison, Madison, WI 
Area:
Protein engineering, biocatalysis, enzymology, chemical biology
Website:
https://www.chem.wisc.edu/users/abuller
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Publications

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Zmich A, Perkins LJ, Bingman C, et al. (2023) Multiplexed Assessment of Promiscuous Non-Canonical Amino Acid Synthase Activity in a Pyridoxal Phosphate-Dependent Protein Family. Acs Catalysis. 13: 11644-11655
Meza A, Campbell ME, Zmich A, et al. (2022) Efficient chemoenzymatic synthesis of α-aryl aldehydes as intermediates in C-C bond forming biocatalytic cascades. Acs Catalysis. 12: 10700-10710
McDonald AD, Bruffy SK, Kasat AT, et al. (2022) Engineering Enzyme Substrate Scope Complementarity for Promiscuous Cascade Synthesis of 1,2-Amino Alcohols. Angewandte Chemie (International Ed. in English)
McDonald AD, Higgins PM, Buller AR. (2022) Substrate multiplexed protein engineering facilitates promiscuous biocatalytic synthesis. Nature Communications. 13: 5242
Ellis JM, Campbell ME, Kumar P, et al. (2022) Biocatalytic synthesis of non-standard amino acids by a decarboxylative aldol reaction. Nature Catalysis. 5: 136-143
Smith JL, Madrigal Harrison I, Bingman C, et al. (2022) Investigation of β-substitution activity of O-acetylserine sulfhydrolase from Citrullus vulgaris. Chembiochem : a European Journal of Chemical Biology
Watkins-Dulaney EJ, Dunham NP, Straathof S, et al. (2021) Asymmetric Alkylation of Ketones Catalyzed by Engineered TrpB. Angewandte Chemie (International Ed. in English)
Kumar P, Meza A, Ellis JM, et al. (2020) l-Threonine Transaldolase Activity Is Enabled by a Persistent Catalytic Intermediate. Acs Chemical Biology
Patel KD, d'Andrea FB, Gaudelli NM, et al. (2019) Structure of a bound peptide phosphonate reveals the mechanism of nocardicin bifunctional thioesterase epimerase-hydrolase half-reactions. Nature Communications. 10: 3868
McDonald A, Perkins L, Buller AR. (2019) Facile in vitro biocatalytic production of diverse tryptamines. Chembiochem : a European Journal of Chemical Biology
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