Adam R Offenbacher, Ph.D.
Affiliations: | 2013 | Chemistry and Biochemistry | Georgia Institute of Technology, Atlanta, GA |
| 2013-2017 | Chemistry | University of California, Berkeley, Berkeley, CA, United States | |
| 2017- | Biochemistry | East Carolina University, Greenville, NC, United States |
Website:
http://www.ecu.edu/cs-cas/chem/Adam-Offenbacher.cfmGoogle:
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Parents
Sign in to add mentor| Bridgette Anne Barry | grad student | 2010 | Georgia Tech | |
| (Protein structural changes and tyrosyl radical-mediated electron transfer reactions in ribonucleotide reductase and model compounds.) | ||||
| Judith Pollock Klinman | post-doc | 2013-2017 | UC Berkeley | |
| (Soybean Lipoxygenase, HDX-MS) | ||||
Children
Sign in to add trainee| Anastasiia Kostenko | grad student | East Carolina University | |
| Kei Ohgo | grad student | East Carolina University | |
| Grega Popovic | grad student | East Carolina University | |
| Daniella Roberts | grad student | East Carolina University | |
| Rachel L. Signorelli | grad student | East Carolina University | |
| Kristin Tyson | grad student | East Carolina University | |
| Chris Whittington | grad student | East Carolina University | |
| Amanda R Ohler | grad student | 2020-2022 | East Carolina University |
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Publications
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| Whittington C, Sharma A, Hill SG, et al. (2024) Impact of -Glycosylation on Protein Structure and Dynamics Linked to Enzymatic C-H Activation in the Lipoxygenase. Biochemistry |
| Ohler A, Taylor PE, Bledsoe JA, et al. (2024) Identification of the Thermal Activation Network in Human 15-Lipoxygenase-2: Divergence from Plant Orthologs and Its Relationship to Hydrogen Tunneling Activation Barriers. Acs Catalysis. 14: 5444-5457 |
| Guevara L, Gouge M, Ohler A, et al. (2023) Effect of solvent viscosity on the activation barrier of hydrogen tunneling in the lipoxygenase reaction. Archives of Biochemistry and Biophysics. 747: 109740 |
| Sharma A, Whittington C, Jabed M, et al. (2023) C Electron Nuclear Double Resonance Spectroscopy-Guided Molecular Dynamics Computations Reveal the Structure of the Enzyme-Substrate Complex of an Active, -Linked Glycosylated Lipoxygenase. Biochemistry |
| Zaragoza JPT, Offenbacher AR, Hu S, et al. (2023) Temporal and spatial resolution of distal protein motions that activate hydrogen tunneling in soybean lipoxygenase. Proceedings of the National Academy of Sciences of the United States of America. 120: e2211630120 |
| Pinelo JEE, Manandhar P, Popovic G, et al. (2023) Systematic mapping of the conformational landscape and dynamism of soluble fibrinogen. Journal of Thrombosis and Haemostasis : Jth |
| Tyson K, Tangtartharakul CB, Zeug M, et al. (2022) Electrochemical and Structural Study of the Buried Tryptophan in Azurin: Effects of Hydration and Polarity on the Redox Potential of W48. The Journal of Physical Chemistry. B |
| Tran M, Signorelli RL, Yamaguchi A, et al. (2022) Biochemical and hydrogen-deuterium exchange studies of the single nucleotide polymorphism Y649C in human platelet 12-lipoxygenase linked to a bleeding disorder. Archives of Biochemistry and Biophysics. 109472 |
| Labrecque CL, Nolan AL, Develin AM, et al. (2022) Membrane-Mimicking Reverse Micelles for High-Resolution Interfacial Study of Proteins and Membranes. Langmuir : the Acs Journal of Surfaces and Colloids. 38: 3676-3686 |
| Popovic G, Kirby NC, Dement TC, et al. (2022) Development of Transient Recombinant Expression and Affinity Chromatography Systems for Human Fibrinogen. International Journal of Molecular Sciences. 23 |