Simone Brixius-Anderko
Affiliations: | 2017- | Medicinal Chemistry | University of Michigan, Ann Arbor, Ann Arbor, MI |
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| Loomis CL, Brixius-Anderko S, Scott EE. (2022) Redox partner adrenodoxin alters cytochrome P450 11B1 ligand binding and inhibition. Journal of Inorganic Biochemistry. 235: 111934 |
| Brixius-Anderko S, Scott EE. (2021) Aldosterone Synthase Structure With Cushing Disease Drug LCI699 Highlights Avenues for Selective CYP11B Drug Design. Hypertension (Dallas, Tex. : 1979). HYPERTENSIONAHA12117 |
| Brixius-Anderko S, Scott EE. (2021) Structural and functional insights into aldosterone synthase interaction with its redox partner protein adrenodoxin. The Journal of Biological Chemistry. 100794 |
| Wróbel TM, Rogova O, Andersen KL, et al. (2020) Discovery of Novel Non-Steroidal Cytochrome P450 17A1 Inhibitors as Potential Prostate Cancer Agents. International Journal of Molecular Sciences. 21 |
| König L, Szczesny S, Brixius-Anderko S, et al. (2020) Mixed-culture fermentation for enhanced C21-hydroxylation of glucocorticoids. Journal of Biotechnology |
| Brixius-Anderko S, Scott EE. (2020) Abstract MP11: Aldosterone Synthase Structure With Cushing’s Disease Drug Osilodrostat Provides Clues For Treatment Of Primary Aldosteronism Hypertension. 76 |
| Brixius-Anderko S, Scott E. (2020) Structural and Functional Insights into Aldosterone Synthase Interaction with Ligands and Redox Partner Proteins for Enhanced Treatment of Hypertension The Faseb Journal. 34: 1-1 |
| Brixius-Anderko S, Scott EE. (2018) Structure of human cortisol-producing cytochrome P450 11B1 bound to the breast cancer drug fadrozole provides insights for drug design. The Journal of Biological Chemistry |
| Malikova J, Brixius-Anderko S, Udhane SS, et al. (2017) CYP17A1 inhibitor abiraterone, an anti-prostate cancer drug, also inhibits the 21-hydroxylase activity of CYP21A2. The Journal of Steroid Biochemistry and Molecular Biology |
| Schiffer L, Müller AR, Hobler A, et al. (2016) Biotransformation of the mineralocorticoid receptor antagonists spironolactone and canrenone by human CYP11B1 and CYP11B2: Characterization of the products and their influence on mineralocorticoid receptor transactivation. The Journal of Steroid Biochemistry and Molecular Biology. 163: 68-76 |