Patrick Porubsky
Affiliations: | 2009 | Medicinal Chemistry | University of Kansas, Lawrence, KS, United States |
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Petrunak EM, DeVore NM, Porubsky PR, et al. (2014) Structures of human steroidogenic cytochrome P450 17A1 with substrates. The Journal of Biological Chemistry. 289: 32952-64 |
Spicer T, Fernandez-Vega V, Chase P, et al. (2014) Identification of Potent and Selective Inhibitors of the Plasmodium falciparum M18 Aspartyl Aminopeptidase (PfM18AAP) of Human Malaria via High-Throughput Screening. Journal of Biomolecular Screening. 19: 1107-1115 |
Motiwala HF, Fehl C, Li SW, et al. (2013) Overcoming product inhibition in catalysis of the intramolecular Schmidt reaction. Journal of the American Chemical Society. 135: 9000-9 |
Dubrovskiy AV, Jain P, Shi F, et al. (2013) Solution-phase synthesis of a diverse library of benzisoxazoles utilizing the [3 + 2] cycloaddition of in situ-generated nitrile oxides and arynes. Acs Combinatorial Science. 15: 193-201 |
Zang Q, Javed S, Hill D, et al. (2012) Automated synthesis of a library of triazolated 1,2,5-thiadiazepane 1,1-dioxides via a double aza-Michael strategy. Acs Combinatorial Science. 14: 456-9 |
Zang Q, Javed S, Porubsky P, et al. (2012) Synthesis of a unique isoindoline/tetrahydroisoquinoline-based tricyclic sultam library utilizing a Heck-aza-Michael strategy. Acs Combinatorial Science. 14: 211-7 |
Porubsky PR, Battaile KP, Scott EE. (2010) Human cytochrome P450 2E1 structures with fatty acid analogs reveal a previously unobserved binding mode. The Journal of Biological Chemistry. 285: 22282-90 |
Porubsky PR, Meneely KM, Scott EE. (2008) Structures of human cytochrome P-450 2E1. Insights into the binding of inhibitors and both small molecular weight and fatty acid substrates. The Journal of Biological Chemistry. 283: 33698-707 |
Porubsky PR, Scott EE, Williams TD. (2008) p-dimethylaminocinnamaldehyde derivatization for colorimetric detection and HPLC-UV/vis-MS/MS identification of indoles. Archives of Biochemistry and Biophysics. 475: 14-7 |
Smith BD, Sanders JL, Porubsky PR, et al. (2007) Structure of the human lung cytochrome P450 2A13. The Journal of Biological Chemistry. 282: 17306-13 |