Stephen Todd Smale

Affiliations: 
1990- Microbiology, Immunology, and Molecular Genetics University of California, Los Angeles, Los Angeles, CA 
Area:
gene regulation during inflammatory and innate immune responses and during lymphocyte development and leukemogenesis
Website:
https://people.healthsciences.ucla.edu/institution/personnel?personnel_id=45693
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Parents

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Robert Tjian grad student 1986 UC Berkeley
 (Simian Virus 40 DNA Replication: A Model for Eukaryotic DNA Synthesis.)
David Baltimore post-doc Whitehead Institute (MIT)

Children

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Patricia Ernst grad student 1996 UCLA
Hans D. Brightbill grad student 2000 UCLA (Cell Biology Tree)
Amy S. Weinmann grad student 2000 UCLA (Cell Biology Tree)
Michelle N. Bradley grad student 2003 UCLA (Cell Biology Tree)
Aaron S. McCarty grad student 2003 UCLA (Cell Biology Tree)
Liang Zhou grad student 2004 UCLA (Cell Biology Tree)
Roger L. Ferrini grad student 2005 UCLA (Cell Biology Tree)
Rupa Sridharan grad student 2006 UCLA (Cell Biology Tree)
Jin Xu grad student 2008 UCLA (Cell Biology Tree)
Scott D. Pope grad student 2009 UCLA (Cell Biology Tree)
Dev M. Bhatt grad student 2011 UCLA (Cell Biology Tree)
Abraham B. Chang grad student 2011 UCLA (Cell Biology Tree)
Kevin R. Doty grad student 2012 UCLA (Cell Biology Tree)
Miguel Edwards grad student 2014 UCLA (Cell Biology Tree)
Justin B. Langerman grad student 2014 UCLA (Cell Biology Tree)
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Publications

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Daly AE, Schiffman A, Hoffmann A, et al. (2024) Examining NF-κB genomic interactions by ChIP-seq and CUT&Tag. Biorxiv : the Preprint Server For Biology
Daly AE, Yeh G, Soltero S, et al. (2024) Selective regulation of a defined subset of inflammatory and immunoregulatory genes by an NF-κB p50-IκBζ pathway. Genes & Development
Purbey PK, Seo J, Paul MK, et al. (2024) Opposing tumor-cell-intrinsic and -extrinsic roles of the IRF1 transcription factor in antitumor immunity. Cell Reports. 43: 114289
Feng AC, Thomas BJ, Purbey PK, et al. (2024) The transcription factor NF-κB orchestrates nucleosome remodeling during the primary response to Toll-like receptor 4 signaling. Immunity
Kagan JC, Rothenberg EV, Weiss A, et al. (2023) Cold Spring Harbor Laboratory 2022: emerging insights and viewpoints in immunology. Trends in Immunology
Lo JH, Edwards M, Langerman J, et al. (2022) Oct4:Sox2 binding is essential for establishing but not maintaining active and silent states of dynamically regulated genes in pluripotent cells. Genes & Development. 36: 1079-1095
Aliyari SR, Ghaffari AA, Pernet O, et al. (2022) Suppressing fatty acid synthase by type I interferon and chemical inhibitors as a broad spectrum anti-viral strategy against SARS-CoV-2. Acta Pharmaceutica Sinica. B
Blair L, Pattison MJ, Chakravarty P, et al. (2022) TPL-2 Inhibits IFN-β Expression via an ERK1/2-TCF-FOS Axis in TLR4-Stimulated Macrophages. Journal of Immunology (Baltimore, Md. : 1950). 208: 941-954
Langerman J, Lopez D, Pellegrini M, et al. (2021) Species-Specific Relationships between DNA and Chromatin Properties of CpG Islands in Embryonic Stem Cells and Differentiated Cells. Stem Cell Reports
Hsieh WY, Zhou QD, York AG, et al. (2020) Toll-Like Receptors Induce Signal-Specific Reprogramming of the Macrophage Lipidome. Cell Metabolism
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