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Amy E. Keating

Affiliations:

Biology

Massachusetts Institute of Technology, Cambridge, MA, United States

Area:

Computational, biophysical, structural and proteomic studies of protein-protein interactions

Website:

https://biology.mit.edu/people/amy_keating

Google:

"Amy E. Keating"

Bio:

http://mit.edu/biology/keating/KeatingLab/Home.html

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Parents

Miguel A. Garcia-Garibay	grad student	1998	UCLA
(Molecular mechanics, quantum mechanics and direct dynamics applied to the study of organic carbene reactivity)
Kendall N. Houk	grad student	1998	UCLA
Peter S. Kim	post-doc	2002	MIT
Bruce Tidor	post-doc	2002	MIT

Children

Orr Ashenberg	grad student		MIT
Christina M Taylor	grad student	1999-2005	MIT
Gevorg Grigoryan	grad student	2007	MIT
Kelly M Elkins	post-doc	2003-2004	MIT
Won Min Park	post-doc	2015-2018	MIT

Collaborators

BETA: Related publications

Publications

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Savinov A, Swanson S, Keating AE, et al. (2023) High-throughput computational discovery of inhibitory protein fragments with AlphaFold. Biorxiv : the Preprint Server For Biology
Ghose DA, Przydzial KE, Mahoney EM, et al. (2023) Marginal specificity in protein interactions constrains evolution of a paralogous family. Proceedings of the National Academy of Sciences of the United States of America. 120: e2221163120
Li AJ, Lu M, Desta I, et al. (2022) Neural Network-Derived Potts Models for Structure-Based Protein Design using Backbone Atomic Coordinates and Tertiary Motifs. Protein Science : a Publication of the Protein Society. e4554
Halpin JC, Whitney D, Rigoldi F, et al. (2022) Molecular determinants of TRAF6 binding specificity suggest that native interaction partners are not optimized for affinity. Protein Science : a Publication of the Protein Society. 31: e4429
Swanson S, Sivaraman V, Grigoryan G, et al. (2022) Tertiary motifs as building blocks for the design of protein-binding peptides. Protein Science : a Publication of the Protein Society. 31: e4322
Hwang T, Parker SS, Hill SM, et al. (2022) Native proline-rich motifs exploit sequence context to target actin-remodeling Ena/VASP protein ENAH. Elife. 11
Frappier V, Keating AE. (2021) Data-driven computational protein design. Current Opinion in Structural Biology. 69: 63-69
Linghu C, Johnson SL, Valdes PA, et al. (2020) Spatial Multiplexing of Fluorescent Reporters for Imaging Signaling Network Dynamics. Cell
Shemesh OA, Linghu C, Piatkevich KD, et al. (2020) Precision Calcium Imaging of Dense Neural Populations via a Cell-Body-Targeted Calcium Indicator. Neuron
Frappier V, Jenson JM, Zhou J, et al. (2019) Tertiary Structural Motif Sequence Statistics Enable Facile Prediction and Design of Peptides that Bind Anti-apoptotic Bfl-1 and Mcl-1. Structure (London, England : 1993)

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