Ryan E. Hibbs, Ph.D.

Affiliations: 
Neurscience University of Texas Southwestern Medical Center, Dallas, TX, United States 
Area:
Ligand-gated ion channel structural biology
Website:
https://www.utsouthwestern.edu/labs/hibbs/
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"Ryan E. Hibbs"
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Parents

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Palmer W. Taylor grad student 2006 UCSD
 (Conformational dynamics of the acetylcholine binding protein, a nicotinic receptor surrogate.)
J. Eric Gouaux post-doc OHSU
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Publications

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Zhu S, Sridhar A, Teng J, et al. (2022) Structural and dynamic mechanisms of GABA receptor modulators with opposing activities. Nature Communications. 13: 4582
Noviello CM, Kreye J, Teng J, et al. (2022) Structural mechanisms of GABA receptor autoimmune encephalitis. Cell. 185: 2469-2477.e13
Rahman MM, Basta T, Teng J, et al. (2022) Structural mechanism of muscle nicotinic receptor desensitization and block by curare. Nature Structural & Molecular Biology
Rahman MM, Worrell BT, Stowell MHB, et al. (2021) Purification of a native nicotinic receptor. Methods in Enzymology. 653: 189-206
Noviello CM, Gharpure A, Mukhtasimova N, et al. (2021) Structure and gating mechanism of the α7 nicotinic acetylcholine receptor. Cell
Kim JJ, Hibbs RE. (2021) Direct Structural Insights into GABA Receptor Pharmacology. Trends in Biochemical Sciences
Kim JJ, Gharpure A, Teng J, et al. (2020) Shared structural mechanisms of general anaesthetics and benzodiazepines. Nature
Rahman MM, Teng J, Worrell BT, et al. (2020) Structure of the Native Muscle-type Nicotinic Receptor and Inhibition by Snake Venom Toxins. Neuron
Gharpure A, Noviello CM, Hibbs RE. (2020) Progress in nicotinic receptor structural biology. Neuropharmacology. 171: 108086
Brams M, Govaerts C, Kambara K, et al. (2020) Modulation of the ligand-gated ion channel (ELIC) and the 5-HT receptor via a common vestibule site. Elife. 9
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