Michael W. Crowder, Ph.D.
Affiliations: | Chemistry and Biochemistry | Miami University (Ohio), Oxford, OH |
Area:
bioinorganic chemistryWebsite:
http://chemistry.muohio.edu/faculty/17-faculty/inorganic-chemistry/5-michael-w-crowderGoogle:
"Michael Crowder"Bio:
http://www.users.miamioh.edu/crowdemw/Crowder_group_webpage/About_Crowder.html
Awards: 2007-09 Volwiler Professor
2006 Sigma Xi Researcher of Year
2000 Miami Distinguished Scholar
Mean distance: 7.93 | S | N | B | C | P |
Parents
Sign in to add mentor| Bruce A. Averill | grad student | 1993 | UVA |
| Stephen J. Benkovic | post-doc | 1995 | Penn State |
Children
Sign in to add trainee| Robert M. Breece | grad student | ||
| Jeffrey J. Brandt | grad student | 2000 | Miami University |
| Patrick A. Crawford | grad student | 2003 | Miami University |
| Gopal R. Periyannan | grad student | 2004 | Miami University |
| Frank C. Golich | grad student | 2005 | Miami University |
| Tara K. Sigdel | grad student | 2005 | Miami University |
| Zishuo Cheng | post-doc | 2016-2020 | Miami University |
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Publications
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| Cheng Z, Aitha M, Thomas CA, et al. (2024) Machine Learning Models Identify Inhibitors of New Delhi Metallo-β-lactamase. Journal of Chemical Information and Modeling |
| Thomas CA, Cheng Z, Bethel CR, et al. (2023) The directed evolution of NDM-1. Antimicrobial Agents and Chemotherapy. e0071423 |
| Legru A, Verdirosa F, Vo-Hoang Y, et al. (2022) Optimization of 1,2,4-Triazole-3-thiones toward Broad-Spectrum Metallo-β-lactamase Inhibitors Showing Potent Synergistic Activity on VIM- and NDM-1-Producing Clinical Isolates. Journal of Medicinal Chemistry |
| Thomas PW, Cho EJ, Bethel CR, et al. (2022) Discovery of an Effective Small-Molecule Allosteric Inhibitor of New Delhi Metallo-β-lactamase (NDM). Acs Infectious Diseases |
| Mehta R, Rivera DD, Reilley DJ, et al. (2021) Visualizing the Dynamic Metalation State of New Delhi Metallo-β-lactamase-1 in Bacteria Using a Reversible Fluorescent Probe. Journal of the American Chemical Society |
| Zhang H, Yang K, Cheng Z, et al. (2021) Spectroscopic and biochemical characterization of metallo-β-lactamase IMP-1 with dicarboxylic, sulfonyl, and thiol inhibitors. Bioorganic & Medicinal Chemistry. 40: 116183 |
| Cheng Z, Bethel CR, Thomas PW, et al. (2021) Carbapenem use is driving the evolution of IMiPenemase (IMP)-1 variants. Antimicrobial Agents and Chemotherapy |
| Mehaffey MR, Ahn YC, Rivera DD, et al. (2020) Elusive structural changes of New Delhi metallo-β-lactamase revealed by ultraviolet photodissociation mass spectrometry. Chemical Science. 11: 8999-9010 |
| Thomas CA, Cheng Z, Yang K, et al. (2020) Probing the mechanisms of inhibition for various inhibitors of metallo-β-lactamases VIM-2 and NDM-1. Journal of Inorganic Biochemistry. 210: 111123 |
| Fullington S, Cheng Z, Thomas C, et al. (2020) An integrated biophysical approach to discovering mechanisms of NDM-1 inhibition for several thiol-containing drugs. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry |