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Sign in to add mentor| Alexandra C. Newton | grad student | 2002-2007 | UCSD (Chemistry Tree) | |
| (PHLPP: A novel family of phosphatases that are critical regulators of intracellular signaling pathways.) | ||||
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Publications
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| Torres-Ayuso P, Katerji M, Mehlich D, et al. (2023) PIM1 targeted degradation prevents the emergence of chemoresistance in prostate cancer. Cell Chemical Biology |
| Torres-Ayuso P, Brognard J. (2022) Degraders: The Ultimate Weapon Against Amplified Driver Kinases in Cancer. Molecular Pharmacology. 101: 191-200 |
| Torres-Ayuso P, An E, Nyswaner KM, et al. (2021) TNIK is a therapeutic target in Lung Squamous Cell Carcinoma and regulates FAK activation through Merlin. Cancer Discovery |
| Hoang VT, Nyswaner K, Torres-Ayuso P, et al. (2020) The protein kinase MAP3K19 phosphorylates MAP2Ks and thereby activates ERK and JNK kinases and increases viability of KRAS-mutant lung cancer cells. The Journal of Biological Chemistry |
| Ayuso PT, An E, Ritt D, et al. (2020) The protein kinase TNIK: a novel druggable target in Lung Squamous Cell Carcinoma with 3q amplification. The Faseb Journal. 34: 1-1 |
| Torres-Ayuso P, Brognard J. (2019) Combing the Cancer Genome for Novel Kinase Drivers and New Therapeutic Targets. Cancers. 11 |
| Prelowska M, Mehlich D, Lazniewski M, et al. (2019) Abstract P3-09-07: The role of MLK4 amplification in progression of triple negative breast cancer Cancer Research |
| Marusiak AA, Prelowska MK, Mehlich D, et al. (2018) Upregulation of MLK4 promotes migratory and invasive potential of breast cancer cells. Oncogene |
| An E, Brognard J. (2018) Orange is the new black: Kinases are the new master regulators of tumor suppression. Iubmb Life |
| Torres-Ayuso P, Brognard J. (2018) Shipping Out MEK Inhibitor Resistance with SHP2 Inhibitors. Cancer Discovery. 8: 1210-1212 |