Leslie E. LaConte, Ph.D.

Affiliations: 
2002 University of Minnesota, Twin Cities, Minneapolis, MN 
Area:
Biochemistry, General Biophysics
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David Dale Thomas grad student 2002 UMN
 (Biochemistry and kinetics of the myosin structural change responsible for force generation in active, spin-labeled muscle fibers.)
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Publications

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LaConte LE, Baker JE, Thomas DD. (2003) Transient kinetics and mechanics of myosin's force-generating rotation in muscle: resolution of millisecond rotational transitions in the spin-labeled myosin light-chain domain. Biochemistry. 42: 9797-803
LaConte LE, Voelz V, Nelson W, et al. (2002) Molecular dynamics simulation of site-directed spin labeling: experimental validation in muscle fibers. Biophysical Journal. 83: 1854-66
Baker JE, LaConte LE, Thomas DD, et al. (2000) Muscle chemistry and force. Biophysical Journal. 79: 1687-8
Baker JE, Brust-Mascher I, LaConte LE, et al. (2000) Mechanochemical coupling in muscle. Biophysical Journal. 78: 2730
Baker JE, LaConte LE, Brust-Mascher I, et al. (1999) Mechanochemical coupling in spin-labeled, active, isometric muscle. Biophysical Journal. 77: 2657-64
Brust-Mascher I, LaConte LE, Baker JE, et al. (1999) Myosin light-chain domain rotates upon muscle activation but not ATP hydrolysis. Biochemistry. 38: 12607-13
Baker JE, Brust-Mascher I, Ramachandran S, et al. (1998) A large and distinct rotation of the myosin light chain domain occurs upon muscle contraction. Proceedings of the National Academy of Sciences of the United States of America. 95: 2944-9
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