David J. Kast, Ph.D.
Affiliations: | 2010 | Biochemistry, Molecular Bio, and Biophysics | University of Minnesota, Twin Cities, Minneapolis, MN |
2010-2017 | Physiology | University of Pennsylvania Perelman School of Medicine | |
2017- | Cell Biology and Physiology | Washington University School of Medicine, Saint Louis |
Area:
Biophysics, Biomechanics, BiochemistryGoogle:
"David Kast"Mean distance: (not calculated yet)
Parents
Sign in to add mentorDavid Dale Thomas | grad student | 2010 | UMN | |
(Phosphorylation-induced structural changes in smooth muscle myosin.) |
Children
Sign in to add traineeVictoria A. Ismail | grad student | 2018- | Washington University School of Medicine in St. Louis (Neurotree) |
BETA: Related publications
See more...
Publications
You can help our author matching system! If you notice any publications incorrectly attributed to this author, please sign in and mark matches as correct or incorrect. |
Kast DJ, Dominguez R. (2019) IRSp53 coordinates AMPK and 14-3-3 signaling to regulate filopodia dynamics and directed cell migration. Molecular Biology of the Cell. mbcE18090600 |
Kast DJ, Dominguez R. (2019) Mechanism of IRSp53 inhibition by 14-3-3. Nature Communications. 10: 483 |
Kast DJ, Dominguez R. (2017) The Cytoskeleton-Autophagy Connection. Current Biology : Cb. 27: R318-R326 |
Kast DJ, Dominguez R. (2015) WHAMM links actin assembly via the Arp2/3 complex to autophagy. Autophagy. 11: 1702-4 |
Kast DJ, Zajac AL, Holzbaur EL, et al. (2015) WHAMM Directs the Arp2/3 Complex to the ER for Autophagosome Biogenesis through an Actin Comet Tail Mechanism. Current Biology : Cb. 25: 1791-7 |
Kast DJ, Yang C, Disanza A, et al. (2014) Mechanism of IRSp53 inhibition and combinatorial activation by Cdc42 and downstream effectors. Nature Structural & Molecular Biology. 21: 413-22 |
Boczkowska M, Rebowski G, Kast DJ, et al. (2014) Structural analysis of the transitional state of Arp2/3 complex activation by two actin-bound WCAs. Nature Communications. 5: 3308 |
Colson BA, Mauseth MA, Kast DJ, et al. (2014) Atomic-Level Visualization of Smooth Muscle Activation by Phosphorylation of the Myosin Regulatory Light Chain Biophysical Journal. 106: 161a-162a |
Turegun B, Kast DJ, Dominguez R. (2013) Subunit Rtt102 controls the conformation of the Arp7/9 heterodimer and its interactions with nucleotide and the catalytic subunit of SWI/SNF remodelers. The Journal of Biological Chemistry. 288: 35758-68 |
Disanza A, Bisi S, Winterhoff M, et al. (2013) CDC42 switches IRSp53 from inhibition of actin growth to elongation by clustering of VASP. The Embo Journal. 32: 2735-50 |