Alan P. Wolffe

Affiliations: 
National Institutes of Health, Bethesda, MD 
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"Alan Wolffe"
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Children

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Genevieve Almouzni post-doc NIH (NICHD) (Cell Biology Tree)
Jeffrey J Hayes post-doc (Evolution Tree)
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Publications

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Snowden AW, Zhang L, Urnov F, et al. (2003) Repression of vascular endothelial growth factor A in glioblastoma cells using engineered zinc finger transcription factors. Cancer Research. 63: 8968-76
Rebar EJ, Huang Y, Hickey R, et al. (2002) Induction of angiogenesis in a mouse model using engineered transcription factors. Nature Medicine. 8: 1427-32
Mutskov VJ, Farrell CM, Wade PA, et al. (2002) The barrier function of an insulator couples high histone acetylation levels with specific protection of promoter DNA from methylation. Genes & Development. 16: 1540-54
Jones PL, Wade PA, Wolffe AP. (2002) Purification of MeCP2-containing deacetylase from Xenopus laevis. Methods in Molecular Biology (Clifton, N.J.). 200: 131-41
Liang Y, Li XY, Rebar EJ, et al. (2002) Activation of vascular endothelial growth factor A transcription in tumorigenic glioblastoma cell lines by an enhancer with cell type-specific DNase I accessibility. The Journal of Biological Chemistry. 277: 20087-94
El-Osta A, Kantharidis P, Zalcberg JR, et al. (2002) Precipitous release of methyl-CpG binding protein 2 and histone deacetylase 1 from the methylated human multidrug resistance gene (MDR1) on activation. Molecular and Cellular Biology. 22: 1844-57
Ren D, Collingwood TN, Rebar EJ, et al. (2002) PPARgamma knockdown by engineered transcription factors: exogenous PPARgamma2 but not PPARgamma1 reactivates adipogenesis. Genes & Development. 16: 27-32
Jones PL, Wade PA, Wolffe AP. (2001) Purification of the MeCP2/histone deacetylase complex from Xenopus laevis. Methods in Molecular Biology (Clifton, N.J.). 181: 297-307
El-Osta A, Wolffe AP. (2001) Analysis of chromatin-immunopurified MeCP2-associated fragments. Biochemical and Biophysical Research Communications. 289: 733-737
Veenstra GJC, Wolffe AP. (2001) Gene-selective developmental roles of general transcription factors. Trends in Biochemical Sciences. 26: 665-671
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