Yiwen Chen
Affiliations: | Bioinformatics & Comp Biology | The University of Texas MD Anderson Cancer Center |
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| Zheng C, Wei Y, Zhang P, et al. (2023) CRISPR-Cas9-based functional interrogation of unconventional translatome reveals human cancer dependency on cryptic non-canonical open reading frames. Nature Structural & Molecular Biology |
| Zhang L, He W, Fu R, et al. (2023) Guide-specific loss of efficiency and off-target reduction with Cas9 variants. Nucleic Acids Research |
| Zheng C, Wei Y, Zhang Q, et al. (2023) Multiomics analyses reveal /YBX1-controlled posttranscriptional circuits promoting glioblastoma tumorigenesis/radioresistance. Science Advances. 9: eadf3984 |
| Zheng C, Wei Y, Zhang P, et al. (2023) CRISPR/Cas9 screen uncovers functional translation of cryptic lncRNA-encoded open reading frames in human cancer. The Journal of Clinical Investigation. 133 |
| Fu R, He W, Dou J, et al. (2022) Systematic decomposition of sequence determinants governing CRISPR/Cas9 specificity. Nature Communications. 13: 474 |
| Sun M, Wang Y, Zheng C, et al. (2021) Systematic functional interrogation of human pseudogenes using CRISPRi. Genome Biology. 22: 240 |
| He W, Wang H, Wei Y, et al. (2021) GuidePro: A multi-source ensemble predictor for prioritizing sgRNAs in CRISPR/Cas9 protein knockouts. Bioinformatics (Oxford, England) |
| Zi Z, Zhang Y, Zhang P, et al. (2019) A Proteomic Connectivity Map for Characterizing the Tumor Adaptive Response to Small Molecule Chemical Perturbagens. Acs Chemical Biology |
| Nguyen TM, Kabotyanski EB, Dou Y, et al. (2018) FGFR1-activated Translation of WNT Pathway Components with Structured 5' UTRs is Vulnerable to Inhibition of EIF4A-dependent Translation Initiation. Cancer Research |
| Zhao N, Cao J, Xu L, et al. (2018) Pharmacological targeting of MYC-regulated IRE1/XBP1 pathway suppresses MYC-driven breast cancer. The Journal of Clinical Investigation |