Paula I. Watnick

Affiliations: 
2006- Harvard Medical School - Boston Children's Hospital 
Area:
Biofilms, host pathogen interactions, vaccines, drug discovery, metabolism
Website:
https://paulawatnicklab.com/
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Children

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Layla Kamareddine grad student 2016-2018 Qatar University
Ece Karatan post-doc 2003-2005 Appalachian State University (Microtree)
Laetitia Houot post-doc 2006-2010 Aix-Marseille Université & CNRS
Patrick Ymele-Leki post-doc 2012 Howard University (E-Tree)
Alexandra E. Purdy post-doc 2008-2012 Amherst College (Marine Ecology Tree)
Audrey Vanhove post-doc 2015-2017 IUT-St. Etienne
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Publications

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Gibson JA, Gebhardt MJ, Santos RERS, et al. (2022) Sequestration of a dual function DNA-binding protein by Vibrio cholerae CRP. Proceedings of the National Academy of Sciences of the United States of America. 119: e2210115119
Jugder BE, Batista JH, Gibson JA, et al. (2022) Vibrio cholerae high cell density quorum sensing activates the host intestinal innate immune response. Cell Reports. 40: 111368
Chen Y, Rudolph S, Longo BN, et al. (2022) Bioengineered 3D tissue model of intestine epithelium with oxygen gradients to sustain human gut microbiome. Advanced Healthcare Materials. e2200447
Pace F, Rudolph SE, Chen Y, et al. (2021) The Short-Chain Fatty Acids Propionate and Butyrate Augment Adherent-Invasive Escherichia coli Virulence but Repress Inflammation in a Human Intestinal Enteroid Model of Infection. Microbiology Spectrum. e0136921
Jugder BE, Kamareddine L, Watnick PI. (2021) Microbiota-derived acetate activates intestinal innate immunity via the Tip60 histone acetyltransferase complex. Immunity
Pace F, Watnick PI. (2020) The Interplay of Sex Steroids, the Immune Response, and the Intestinal Microbiota. Trends in Microbiology
Vanhove AS, Jugder BE, Barraza D, et al. (2020) Methionine Availability in the Arthropod Intestine Is Elucidated through Identification of Vibrio cholerae Methionine Acquisition Systems. Applied and Environmental Microbiology. 86
Jugder BE, Watnick PI. (2020) Vibrio cholerae Sheds Its Coat to Make Itself Comfortable in the Gut. Cell Host & Microbe. 27: 161-163
Watnick PI, Jugder BE. (2020) Microbial Control of Intestinal Homeostasis via Enteroendocrine Cell Innate Immune Signaling. Trends in Microbiology. 28: 141-149
Liao J, Xu G, Mevers EE, et al. (2018) A high-throughput, whole cell assay to identify compounds active against carbapenem-resistant Klebsiella pneumoniae. Plos One. 13: e0209389
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