Anisa Scott

Pharmacology University of Virginia, Charlottesville, VA 
"Anisa Scott"
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Fadden P, Huang KH, Veal JM, et al. (2010) Application of chemoproteomics to drug discovery: identification of a clinical candidate targeting hsp90. Chemistry & Biology. 17: 686-94
Putcha P, Danzer KM, Kranich LR, et al. (2010) Brain-permeable small-molecule inhibitors of Hsp90 prevent alpha-synuclein oligomer formation and rescue alpha-synuclein-induced toxicity. The Journal of Pharmacology and Experimental Therapeutics. 332: 849-57
Rice JW, Veal JM, Barabasz A, et al. (2009) Targeting of multiple signaling pathways by the Hsp90 inhibitor SNX-2112 in EGFR resistance models as a single agent or in combination with erlotinib. Oncology Research. 18: 229-42
Huang KH, Veal JM, Fadden RP, et al. (2009) Discovery of novel 2-aminobenzamide inhibitors of heat shock protein 90 as potent, selective and orally active antitumor agents. Journal of Medicinal Chemistry. 52: 4288-305
Chandarlapaty S, Sawai A, Ye Q, et al. (2008) SNX2112, a synthetic heat shock protein 90 inhibitor, has potent antitumor activity against HER kinase-dependent cancers. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 240-8
Barabasz A, Foley B, Otto JC, et al. (2006) The use of high-content screening for the discovery and characterization of compounds that modulate mitotic index and cell cycle progression by differing mechanisms of action. Assay and Drug Development Technologies. 4: 153-63
Steed P, Huang H, Fadden P, et al. (2006) 545 POSTER SNX-2112: a novel, selective, potent small molecule inhibitor of Hsp90 with unique pharmacodynamic properties European Journal of Cancer Supplements. 4: 165
Scott A, Haystead CMM, Haystead TAJ. (1995) Purification of a 12,020-dalton protein that enhances the activation of mitogen-activated protein (MAP) kinase by MAP kinase kinase Journal of Biological Chemistry. 270: 24540-24547
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