Scott Scarneo

2018- Pharmacology Duke University, Durham, NC 
"Scott Scarneo"
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Timothy Arthur James Haystead grad student 2018- Duke
Derek C Molliver grad student 2015-2017 University of New England (Neurotree)
 (MS Biology Thesis: Co-mentored with Dr. Kat Hanlon)
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Haystead T, Lee E, Cho K, et al. (2023) Investigation of SARS-CoV-2 individual proteins reveals the in vitro and in vivo immunogenicity of membrane protein. Scientific Reports. 13: 22873
Freeze R, Yang KW, Haystead T, et al. (2023) Delineation of the distinct inflammatory signaling roles of TAK1 and JAK1/3 in the CIA model of rheumatoid arthritis. Pharmacology Research & Perspectives. 11: e01124
Bale S, Verma P, Yalavarthi B, et al. (2023) Pharmacological inhibition of TAK1 prevents and induces regression of experimental organ fibrosis. Jci Insight
Scarneo S, Zhang X, Wang Y, et al. (2023) Transforming growth factor-β-activated kinase 1 (TAK1) mediates chronic pain and cytokine production in mouse models of inflammatory, neuropathic, and primary pain. The Journal of Pain
Scarneo SA, Smith AP, Favret J, et al. (2022) Expression of membrane Hsp90 is a molecular signature of T cell activation. Scientific Reports. 12: 18091
Scarneo S, Hughes P, Freeze R, et al. (2022) Development and Efficacy of an Orally Bioavailable Selective TAK1 Inhibitor for the Treatment of Inflammatory Arthritis. Acs Chemical Biology
Wang Y, Scarneo SA, Kim SH, et al. (2021) Expression of ectopic heat shock protein 90 in male and female primary afferent nociceptors regulates inflammatory pain. Pain
Totzke J, Scarneo SA, Yang KW, et al. (2020) TAK1: a potent tumour necrosis factor inhibitor for the treatment of inflammatory diseases. Open Biology. 10: 200099
Scarneo SA, Yang KW, Roques JR, et al. (2020) TAK1 regulates the tumor microenvironment through inflammatory, angiogenetic and apoptotic signaling cascades. Oncotarget. 11: 1961-1970
Scarneo SA, Hughes PF, Yang KW, et al. (2019) A highly selective inhibitor of interleukin-1 receptor-associated kinases 1/4 (IRAK-1/4) delineates the distinct signaling roles of IRAK-1/4 and the TAK1 kinase. The Journal of Biological Chemistry
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