Scott Scarneo

Affiliations: 
2018- Pharmacology Duke University, Durham, NC 
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Parents

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Timothy Arthur James Haystead grad student 2018- Duke
Derek C Molliver grad student 2015-2017 University of New England (Neurotree)
 (MS Biology Thesis: Co-mentored with Dr. Kat Hanlon)
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Publications

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Freeze R, Hughes P, Haystead T, et al. (2024) Transforming Growth Factor-β-Activated Kinase 1 (TAK1) Alleviates Inflammatory Joint Pain in Osteoarthritis and Gouty Arthritis Preclinical Models. Journal of Pain Research. 17: 2287-2298
Damhofer H, Tatar T, Southgate B, et al. (2024) TAK1 inhibition leads to RIPK1-dependent apoptosis in immune-activated cancers. Cell Death & Disease. 15: 273
Haystead T, Lee E, Cho K, et al. (2023) Investigation of SARS-CoV-2 individual proteins reveals the in vitro and in vivo immunogenicity of membrane protein. Scientific Reports. 13: 22873
Freeze R, Yang KW, Haystead T, et al. (2023) Delineation of the distinct inflammatory signaling roles of TAK1 and JAK1/3 in the CIA model of rheumatoid arthritis. Pharmacology Research & Perspectives. 11: e01124
Bale S, Verma P, Yalavarthi B, et al. (2023) Pharmacological inhibition of TAK1 prevents and induces regression of experimental organ fibrosis. Jci Insight
Scarneo S, Zhang X, Wang Y, et al. (2023) Transforming growth factor-β-activated kinase 1 (TAK1) mediates chronic pain and cytokine production in mouse models of inflammatory, neuropathic, and primary pain. The Journal of Pain
Scarneo SA, Smith AP, Favret J, et al. (2022) Expression of membrane Hsp90 is a molecular signature of T cell activation. Scientific Reports. 12: 18091
Scarneo S, Hughes P, Freeze R, et al. (2022) Development and Efficacy of an Orally Bioavailable Selective TAK1 Inhibitor for the Treatment of Inflammatory Arthritis. Acs Chemical Biology
Wang Y, Scarneo SA, Kim SH, et al. (2021) Expression of ectopic heat shock protein 90 in male and female primary afferent nociceptors regulates inflammatory pain. Pain
Totzke J, Scarneo SA, Yang KW, et al. (2020) TAK1: a potent tumour necrosis factor inhibitor for the treatment of inflammatory diseases. Open Biology. 10: 200099
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