David Loiselle

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2007- Pharmacology Duke University, Durham, NC 
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"David Loiselle"
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Smith AD, Garcia-Santamarina S, Ralle M, et al. (2021) Transcription factor-driven alternative localization of Cryptococcus neoformans superoxide dismutase. The Journal of Biological Chemistry. 100391
Dong B, Jaeger AM, Hughes PF, et al. (2020) Targeting therapy-resistant prostate cancer via a direct inhibitor of the human heat shock transcription factor 1. Science Translational Medicine. 12
Lu KY, Pasaje CFA, Srivastava T, et al. (2020) Phosphatidylinositol 3-phosphate and Hsp70 protect from heat-induced cell death. Elife. 9
Buccilli MJ, Ilacqua AN, Han M, et al. (2019) Copine A Interacts with Actin Filaments and Plays a Role in Chemotaxis and Adhesion. Cells. 8
Sager RA, Woodford MR, Backe SJ, et al. (2019) Post-translational Regulation of FNIP1 Creates a Rheostat for the Molecular Chaperone Hsp90. Cell Reports. 26: 1344-1356.e5
Scarneo SA, Mansourati A, Eibschutz LS, et al. (2018) Genetic and pharmacological validation of TAK1 inhibition in macrophages as a therapeutic strategy to effectively inhibit TNF secretion. Scientific Reports. 8: 17058
Dushukyan N, Dunn DM, Sager RA, et al. (2017) Phosphorylation and Ubiquitination Regulate Protein Phosphatase 5 Activity and Its Prosurvival Role in Kidney Cancer. Cell Reports. 21: 1883-1895
Kulkarni MM, Ratcliff AN, Bhat M, et al. (2017) Cellular fatty acid synthase is required for late stages of HIV-1 replication. Retrovirology. 14: 45
Totzke J, Gurbani D, Raphemot R, et al. (2017) Takinib, a Selective TAK1 Inhibitor, Broadens the Therapeutic Efficacy of TNF-α Inhibition for Cancer and Autoimmune Disease. Cell Chemical Biology. 24: 1029-1039.e7
Crowe LB, Hughes PF, Alcorta DA, et al. (2017) A fluorescent Hsp90 probe demonstrates the unique association between extracellular Hsp90 and malignancy in vivo. Acs Chemical Biology
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