Mario D. Bachi

Affiliations: 
Department of Organic Chemistry Weizmann Institute of Science, Rehovot, Israel 
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"Mario Bachi"
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O'Neill PM, Verissimo E, Ward SA, et al. (2006) Diels-Alder/thiol-olefin co-oxygenation approach to antimalarials incorporating the 2,3-dioxabicyclo[3.3.1]nonane pharmacophore. Bioorganic & Medicinal Chemistry Letters. 16: 2991-5
Szpilman AM, Korshin EE, Rozenberg H, et al. (2005) Total syntheses of Yingzhaosu A and of its C(14)-epimer including the first evaluation of their antimalarial and cytotoxic activities. The Journal of Organic Chemistry. 70: 3618-32
O'Neill PM, Stocks PA, Pugh MD, et al. (2004) Design and synthesis of endoperoxide antimalarial prodrug models. Angewandte Chemie (International Ed. in English). 43: 4193-7
Korshin EE, Bilokin YV, Zheng H, et al. (2004) Efficient stereoselective alkenylation through a homolytic domino reaction involving a 1,5 sulfur-to-carbon translocation. Journal of the American Chemical Society. 126: 2708-9
Bachi MD, Korshin EE, Hoos R, et al. (2003) A short synthesis and biological evaluation of potent and nontoxic antimalarial bridged bicyclic beta-sulfonyl-endoperoxides. Journal of Medicinal Chemistry. 46: 2516-33
Korshin EE, Hoos R, Szpilman AM, et al. (2002) An efficient synthesis of bridged-bicyclic peroxides structurally related to antimalarial yingzhaosu A based on radical co-oxygenation of thiols and monoterpenes Tetrahedron. 58: 2449-2469
Szpilman AM, Korshin EE, Hoos R, et al. (2001) Iron(II)-induced degradation of antimalarial beta-sulfonyl endoperoxides: evidence for the generation of potentially cytotoxic carbocations. The Journal of Organic Chemistry. 66: 6531-40
Bachi MD, Korshin EE, Ploypradith P, et al. (1998) Synthesis and in vitro antimalarial activity of sulfone endoperoxides. Bioorganic & Medicinal Chemistry Letters. 8: 903-8
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