Tsan Sam Xiao
Affiliations: | 1995-2001 | University of Texas Southwestern Medical Center, Dallas, TX, United States | |
| 2001-2006 | Harvard Medical School, Boston, MA, United States | ||
| 2006-2014 | National Institutes of Health, National Institute of Allergy and Infectious Diseases | ||
| 2014- | Case Western Reserve University School of Medicine, Cleveland, OH, United States |
Area:
Inflammasome, pyroptosis, innate immunityWebsite:
https://case.edu/medicine/pathology/faculty/tsan-sam-xiaoGoogle:
"Tsan Xiao"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Stephen R. Sprang | grad student | 1995-2000 | University of Texas Southwester Medical Center |
| Stephen R. Sprang | post-doc | 2000-2001 | University of Texas Southwester Medical Center |
| Timothy A. Springer | post-doc | 2001-2006 | Harvard Medical School |
| Jia-huai Wang | post-doc | 2001-2006 | Harvard Medical School, Dana Farber Cancer Institute |
Children
Sign in to add trainee| Jie Yang | grad student | 2015-2019 | Case Western Medical School |
| Rui Yang | grad student | 2017-2019 | Case Western Medical School |
| Tinghe Wu | post-doc | 2007-2008 | National Institutes of Health, National Institute of Allergy and Infectious Diseases |
| Ruiling Mu | post-doc | 2006-2011 | National Institutes of Health, National Institute of Allergy and Infectious Diseases |
| Greg A. Snyder | post-doc | 2006-2011 | National Institutes of Health, National Institute of Allergy and Infectious Diseases |
| Tengchuan Jin | post-doc | 2008-2014 | National Institutes of Health, National Institute of Allergy and Infectious Diseases |
| Watchalee Chuenchor | post-doc | 2011-2014 | National Institutes of Health, National Institute of Allergy and Infectious Diseases |
| Geoffrey E. Ravilious | post-doc | 2012-2014 | National Institutes of Health, National Institute of Allergy and Infectious Diseases (Physics Tree) |
| Zhonghua Liu | post-doc | 2015-2020 | Case Western Medical School |
Collaborators
Sign in to add collaborator| Derek Abbott | collaborator | 2014- | Case Western Medical School |
| George R. Dubyak | collaborator | 2014- | Case Western Medical School (Physics Tree) |
| Eckhard Jankowsky | collaborator | 2014- | Case Western Medical School |
BETA: Related publications
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Publications
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| Li Y, Liu Z, Zhao Y, et al. (2022) PD-L1 expression is regulated by ATP-binding of the ERBB3 pseudokinase domain. Genes & Diseases. 10: 1702-1713 |
| Xu Z, Deng S, Huang Y, et al. (2022) The CARD8 T60 variant associates with NLRP1 and negatively regulates its activation. Frontiers in Immunology. 13: 1047922 |
| Basavarajappa SC, Liu AR, Bruchez A, et al. (2022) Trimeric Receptor Binding Domain of SARS-CoV-2 Acts as a Potent Inhibitor of ACE2 Receptor-Mediated Viral Entry. Iscience. 104716 |
| Zhang Q, Liu W, Wang H, et al. (2022) TH17 cells promote CNS inflammation by sensing danger signals via Mincle. Nature Communications. 13: 2406 |
| Liu Z, Xiao TS. (2021) Partners with a killer: Metabolic signaling promotes inflammatory cell death. Cell. 184: 4374-4376 |
| Fan X, Jiang J, Zhao D, et al. (2021) Structural mechanism of DNA recognition by the p204 HIN domain. Nucleic Acids Research |
| Liu Z, Wang C, Yang J, et al. (2020) Caspase-1 Engages Full-Length Gasdermin D through Two Distinct Interfaces That Mediate Caspase Recruitment and Substrate Cleavage. Immunity |
| Srinivasan S, Liu Z, Chuenchor W, et al. (2020) Function of Auxiliary Domains of the DEAH/RHA Helicase DHX36 in RNA Remodeling. Journal of Molecular Biology |
| Rathkey JK, Xiao TS, Abbott DW. (2020) Human polymorphisms in Gsdmd alter the inflammatory response. The Journal of Biological Chemistry |
| Liu Z, Wang C, Yang J, et al. (2019) Crystal Structures of the Full-Length Murine and Human Gasdermin D Reveal Mechanisms of Autoinhibition, Lipid Binding, and Oligomerization. Immunity |