Zhonghua Liu

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2015-2020 Pathology Case Western Reserve University School of Medicine, Cleveland, OH, United States 
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"Zhonghua Liu"
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Liu Z, Li S, Wang C, et al. (2024) Palmitoylation at a conserved cysteine residue facilitates gasdermin D-mediated pyroptosis and cytokine release. Proceedings of the National Academy of Sciences of the United States of America. 121: e2400883121
Busscher BM, Befekadu HB, Liu Z, et al. (2023) SARS-CoV-2 ORF3a-Mediated NF-κB Activation Is Not Dependent on TRAF-Binding Sequence. Viruses. 15
Li S, Bracey S, Liu Z, et al. (2023) Regulation of gasdermins in pyroptosis and cytokine release. Advances in Immunology. 158: 75-106
Li Y, Liu Z, Zhao Y, et al. (2022) PD-L1 expression is regulated by ATP-binding of the ERBB3 pseudokinase domain. Genes & Diseases. 10: 1702-1713
Basavarajappa SC, Liu AR, Bruchez A, et al. (2022) Trimeric Receptor Binding Domain of SARS-CoV-2 Acts as a Potent Inhibitor of ACE2 Receptor-Mediated Viral Entry. Iscience. 104716
Liu Z, Xiao TS. (2021) Partners with a killer: Metabolic signaling promotes inflammatory cell death. Cell. 184: 4374-4376
Liu Z, Wang C, Yang J, et al. (2020) Caspase-1 Engages Full-Length Gasdermin D through Two Distinct Interfaces That Mediate Caspase Recruitment and Substrate Cleavage. Immunity
Srinivasan S, Liu Z, Chuenchor W, et al. (2020) Function of Auxiliary Domains of the DEAH/RHA Helicase DHX36 in RNA Remodeling. Journal of Molecular Biology
Liu Z, Wang C, Yang J, et al. (2019) Crystal Structures of the Full-Length Murine and Human Gasdermin D Reveal Mechanisms of Autoinhibition, Lipid Binding, and Oligomerization. Immunity
Rathkey JK, Zhao J, Liu Z, et al. (2018) Chemical disruption of the pyroptotic pore-forming protein gasdermin D inhibits inflammatory cell death and sepsis. Science Immunology. 3
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