Zhen Wang
Affiliations: | Albert Einstein College of Medicine, New York, New York, United States |
Area:
Enzyme Catalysis; Protein Dynamics; Transition State AnalysisGoogle:
"Zhen Wang"Mean distance: 9.7 | S | N | B | C | P |
Parents
Sign in to add mentor| Amnon Kohen | grad student | 2007-2012 | University of Iowa | |
| (Catalytic mechanisms of thymidylate synthases: Bringing experiments and computations together.) | ||||
| Vern L. Schramm | post-doc | 2013- | Albert Einstein | |
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Publications
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| Chen S, Kapilashrami K, Senevirathne C, et al. (2019) Substrate-differentiated Transition States of SET7/9-catalyzed Lysine Methylation. Journal of the American Chemical Society |
| Zhang L, You L, Yang X, et al. (2018) Hotspot relaxation time of NbN superconducting nanowire single-photon detectors on various substrates. Scientific Reports. 8: 1486 |
| Abeysinghe T, Hong B, Wang Z, et al. (2016) Preserved hydride transfer mechanism in evolutionarily divergent thymidylate synthases. Current Topics in Biochemical Research. 17: 19-30 |
| Linscott JA, Kapilashrami K, Wang Z, et al. (2016) Kinetic isotope effects reveal early transition state of protein lysine methyltransferase SET8. Proceedings of the National Academy of Sciences of the United States of America |
| Wang Z, Chang EP, Schramm VL. (2016) "Triple Isotope Effects Support Concerted Hydride and Proton Transfer and Promoting Vibrations in Human Heart Lactate Dehydrogenase". Journal of the American Chemical Society |
| Du Q, Wang Z, Schramm VL. (2016) Human DNMT1 transition state structure. Proceedings of the National Academy of Sciences of the United States of America |
| Wang Z, Antoniou D, Schwartz SD, et al. (2015) "Hydride Transfer in DHFR by Transition Path Sampling, Kinetic Isotope Effects and Heavy Enzyme Studies". Biochemistry |
| Hong B, Li C, Wang Z, et al. (2015) Enantioselective Total Synthesis of (-)-Incarviatone A. Journal of the American Chemical Society. 137: 11946-9 |
| Wang Z, Singh P, Czekster CM, et al. (2014) Protein mass-modulated effects in the catalytic mechanism of dihydrofolate reductase: beyond promoting vibrations. Journal of the American Chemical Society. 136: 8333-41 |
| Wang Z, Sapienza PJ, Abeysinghe T, et al. (2013) Mg2+ binds to the surface of thymidylate synthase and affects hydride transfer at the interior active site. Journal of the American Chemical Society. 135: 7583-92 |