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Thomas E. Ellenberger

Affiliations: 
Biochemistry and Molecular Biophysics Washington University, Saint Louis, St. Louis, MO 
Website:
http://news.wustl.edu/news/Pages/6297.aspx
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Parents

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Stephen M. Beverley grad student 1989 Harvard Medical School
 (Gene amplification and pleiotropic drug resistance in the human parasite Leishmania major)

Children

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Albert Lau grad student 1999 Harvard
Sylvie Doublié post-doc 1995-1998 Harvard Medical School
Michael R. Sawaya post-doc 1997-2000 Harvard
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Publications

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Pascal JM, Ellenberger T. (2015) The rise and fall of poly(ADP-ribose): An enzymatic perspective. Dna Repair. 32: 10-6
Ghisays F, Brace CS, Yackly SM, et al. (2015) The N-Terminal Domain of SIRT1 Is a Positive Regulator of Endogenous SIRT1-Dependent Deacetylation and Transcriptional Outputs. Cell Reports
Kim IK, Stegeman RA, Brosey CA, et al. (2015) A quantitative assay reveals ligand specificity of the DNA scaffold repair protein XRCC1 and efficient disassembly of complexes of XRCC1 and the poly(ADP-ribose) polymerase 1 by poly(ADP-ribose) glycohydrolase Journal of Biological Chemistry. 290: 3775-3783
Cotner-Gohara E, Kim IK, Hammel M, et al. (2010) Human DNA ligase III recognizes DNA ends by dynamic switching between two DNA-bound states Biochemistry. 49: 6165-6176
Han Z, Pinkner JS, Ford B, et al. (2010) Structure-based drug design and optimization of mannoside bacterial FimH antagonists. Journal of Medicinal Chemistry. 53: 4779-92
Perry JJP, Cotner-Gohara E, Ellenberger T, et al. (2010) Structural dynamics in DNA damage signaling and repair Current Opinion in Structural Biology. 20: 283-294
Orelli B, McClendon TB, Tsodikov OV, et al. (2010) The XPA-binding domain of ERCC1 is required for nucleotide excision repair but not other DNA repair pathways. The Journal of Biological Chemistry. 285: 3705-12
Antony E, Tomko EJ, Xiao Q, et al. (2009) Srs2 disassembles Rad51 filaments by a protein-protein interaction triggering ATP turnover and dissociation of Rad51 from DNA. Molecular Cell. 35: 105-15
Etzion Y, Hackett A, Proctor BM, et al. (2009) An unbiased chemical biology screen identifies agents that modulate uptake of oxidized LDL by macrophages Circulation Research. 105: 148-157
Song W, Pascal JM, Ellenberger T, et al. (2009) The DNA binding domain of human DNA ligase I interacts with both nicked DNA and the DNA sliding clamps, PCNA and hRad9-hRad1-hHus1. Dna Repair. 8: 912-9
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