Melissa L. Zastrow

2017- Chemistry University of Houston, Houston, TX, United States 
bioinorganic chemistry, inorganic cell biology
"Melissa Zastrow"
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Zastrow ML, Huang Z, Lippard SJ. (2020) HaloTag-based hybrid targetable and ratiometric sensors for intracellular zinc. Acs Chemical Biology
Ruckthong L, Zastrow ML, Stuckey JA, et al. (2016) A Crystallographic Examination of Predisposition versus Preorganization in de Novo Designed Metalloproteins. Journal of the American Chemical Society
Zastrow ML, Radford RJ, Chyan W, et al. (2016) Reaction-Based Probes for Imaging Mobile Zinc in Live Cells and Tissues. Acs Sensors. 1: 32-39
Anderson CT, Radford RJ, Zastrow ML, et al. (2015) Modulation of extrasynaptic NMDA receptors by synaptic and tonic zinc. Proceedings of the National Academy of Sciences of the United States of America. 112: E2705-14
Rivera-Fuentes P, Wrobel AT, Zastrow ML, et al. (2015) A Far-Red Emitting Probe for Unambiguous Detection of Mobile Zinc in Acidic Vesicles and Deep Tissue. Chemical Science (Royal Society of Chemistry : 2010). 6: 1944-1948
Yu F, Cangelosi VM, Zastrow ML, et al. (2014) Protein design: toward functional metalloenzymes. Chemical Reviews. 114: 3495-578
Zastrow ML, Pecoraro VL. (2014) Designing hydrolytic zinc metalloenzymes. Biochemistry. 53: 957-78
Zastrow ML, Pecoraro VL. (2013) Designing functional metalloproteins: from structural to catalytic metal sites. Coordination Chemistry Reviews. 257: 2565-2588
Zastrow ML, Pecoraro VL. (2013) Influence of active site location on catalytic activity in de novo-designed zinc metalloenzymes. Journal of the American Chemical Society. 135: 5895-903
Zastrow ML, Peacock AF, Stuckey JA, et al. (2012) Hydrolytic catalysis and structural stabilization in a designed metalloprotein. Nature Chemistry. 4: 118-23
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