Andrew J. Mitchell
Affiliations: | 2017-2019 | Whitehead Institute for Biomedical Research, Cambridge, MA, United States | |
| 2019-2023 | Ginkgo Bioworks | ||
| 2023- | Moderna |
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Parents
Sign in to add mentor| Amie K. Boal | grad student | 2013-2017 | Penn State |
| Jing-Ke Weng | post-doc | 2017-2019 | Whitehead Institute for Biomedical Research |
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Publications
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| Kim CY, Mitchell AJ, Kastner DW, et al. (2023) Emergence of a proton exchange-based isomerization and lactonization mechanism in the plant coumarin synthase COSY. Nature Communications. 14: 597 |
| Kim CY, Mitchell AJ, Glinkerman CM, et al. (2020) The chloroalkaloid (-)-acutumine is biosynthesized via a Fe(II)- and 2-oxoglutarate-dependent halogenase in Menispermaceae plants. Nature Communications. 11: 1867 |
| Zhang B, Rajakovich LJ, Van Cura D, et al. (2019) Substrate-triggered Formation of a Peroxo-Fe(III/III) Intermediate during Fatty Acid Decarboxylation by UndA. Journal of the American Chemical Society |
| Levsh O, Pluskal T, Carballo V, et al. (2019) Independent evolution of rosmarinic acid biosynthesis in two sister families under the Lamiids clade of flowering plants. The Journal of Biological Chemistry |
| Christ B, Xu C, Xu M, et al. (2019) Repeated evolution of cytochrome P450-mediated spiroketal steroid biosynthesis in plants. Nature Communications. 10: 3206 |
| Rajakovich L, Pandelia ME, Mitchell AJ, et al. (2019) A new microbial pathway for organophosphonate degradation catalyzed by two previously misannotated non-heme-iron oxygenases. Biochemistry |
| Ng TL, Rohac R, Mitchell AJ, et al. (2019) An N-nitrosating metalloenzyme constructs the pharmacophore of streptozotocin. Nature. 566: 94-99 |
| Mitchell AJ, Weng JK. (2019) Unleashing the synthetic power of plant oxygenases: from mechanism to application. Plant Physiology |
| Dunham NP, Mitchell AJ, Del Río Pantoja JM, et al. (2018) α-Amine Desaturation of d-Arginine by the Iron(II)- and 2-(Oxo)glutarate-Dependent l-Arginine 3-Hydroxylase, VioC. Biochemistry |
| Ban Z, Qin H, Mitchell AJ, et al. (2018) Noncatalytic chalcone isomerase-fold proteins in are auxiliary components in prenylated flavonoid biosynthesis. Proceedings of the National Academy of Sciences of the United States of America |