Richard J Youle, PhD

Biochemistry National Institute of Neurological Disorders and Stroke, Bethesda, MD, United States 
Cell biology; Biochemistry
"Richard J Youle"
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Sarraf SA, Sideris DP, Giagtzoglou N, et al. (2019) PINK1/Parkin Influences Cell Cycle by Sequestering TBK1 at Damaged Mitochondria, Inhibiting Mitosis. Cell Reports. 29: 225-235.e5
Vargas JNS, Wang C, Bunker E, et al. (2019) Spatiotemporal Control of ULK1 Activation by NDP52 and TBK1 during Selective Autophagy. Molecular Cell
Sekine S, Wang C, Sideris DP, et al. (2019) Reciprocal Roles of Tom7 and OMA1 during Mitochondrial Import and Activation of PINK1. Molecular Cell
Ader NR, Hoffmann PC, Ganeva I, et al. (2019) Molecular and topological reorganizations in mitochondrial architecture interplay during Bax-mediated steps of apoptosis. Elife. 8
Samstag CL, Hoekstra JG, Huang CH, et al. (2018) Deleterious mitochondrial DNA point mutations are overrepresented in Drosophila expressing a proofreading-defective DNA polymerase γ. Plos Genetics. 14: e1007805
Sliter DA, Martinez J, Hao L, et al. (2018) Parkin and PINK1 mitigate STING-induced inflammation. Nature
Le Guerroué F, Youle RJ. (2018) Active state of Parkin. Nature Structural & Molecular Biology
Sarraf SA, Youle RJ. (2018) Parkin mediates mitophagy during beige-to-white fat conversion. Science Signaling. 11
Yamano K, Wang C, Sarraf SA, et al. (2018) Endosomal Rab cycles regulate Parkin-mediated mitophagy. Elife. 7
Sekine S, Youle RJ. (2018) PINK1 import regulation; a fine system to convey mitochondrial stress to the cytosol. Bmc Biology. 16: 2
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