Joel L. Sussman

Structural Biology Weizmann Institute of Science, Rehovot, Israel 
3D structure/function of nervous system proteins
"Joel L. Sussman"

Mean distance: 8.62


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Cyrus Levinthal grad student 1965-1972 MIT
Sung-Hou Kim research scientist 1972-1976 Duke


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Jan M.L. Martin collaborator Weizmann Institute
Israel Silman collaborator Weizmann Institute (Neurotree)
 (Long-term collaborator)
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Silman I, Shnyrov VL, Ashani Y, et al. (2021) Torpedo californica acetylcholinesterase is stabilized by binding of a divalent metal ion to a novel and versatile 4D motif. Protein Science : a Publication of the Protein Society
Sussman JL, Silman I. (2020) Computational studies on cholinesterases: Strengthening our understanding of the integration of structure, dynamics and function. Neuropharmacology. 179: 108265
Orengo C, Velankar S, Wodak S, et al. (2020) A community proposal to integrate structural bioinformatics activities in ELIXIR (3D-Bioinfo Community). F1000research. 9
Nachon F, Rosenberry TL, Silman I, et al. (2020) A Second Look at the Crystal Structures of Acetylcholinesterase in Complex with Tacrine Derivatives Provides Insights Concerning Catalytic Intermediates and the Design of Specific Insecticides. Molecules (Basel, Switzerland). 25
Toker L, Silman I, Zeev-Ben-Mordehai T, et al. (2020) Polyproline-rich peptides associated with Torpedo californica acetylcholinesterase tetramers. Chemico-Biological Interactions. 109007
Orengo C, Velankar S, Wodak S, et al. (2020) A community proposal to integrate structural bioinformatics activities in ELIXIR (3D-Bioinfo Community) F1000research. 9: 278
Ben-David M, Soskine M, Dubovetskyi A, et al. (2019) Enzyme neo- versus re-functionalization - an epistatic ratchet versus a smooth reversible transition. Molecular Biology and Evolution
Chandar NB, Efremenko I, Silman I, et al. (2019) Molecular dynamics simulations of the interaction of Mouse and Torpedo acetylcholinesterase with covalent inhibitors explain their differential reactivity: Implications for drug design. Chemico-Biological Interactions
Novichkova DA, Lushchekina SV, Dym O, et al. (2019) The four-helix bundle in cholinesterase dimers: Structural and energetic determinants of stability. Chemico-Biological Interactions
Oukoloff K, Coquelle N, Bartolini M, et al. (2019) Design, biological evaluation and X-ray crystallography of nanomolar multifunctional ligands targeting simultaneously acetylcholinesterase and glycogen synthase kinase-3. European Journal of Medicinal Chemistry. 168: 58-77
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