Jean-Paul Behr, Ph.D

Université Louis Pasteur, Strasbourg 
Chemistry, Nucleic acids, Transfection
"Jean-Paul Behr"
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Nothisen M, Perche-Létuvée P, Behr JP, et al. (2018) Cationic Oligospermine-Oligonucleotide Conjugates Provide Carrier-free Splice Switching in Monolayer Cells and Spheroids. Molecular Therapy. Nucleic Acids. 13: 483-492
Nothisen M, Bagilet J, Behr JP, et al. (2016) Structure Tuning of Cationic Oligospermine-siRNA Conjugates for Carrier-Free Gene Silencing. Molecular Pharmaceutics
Bonnet ME, Gossart JB, Benoit E, et al. (2013) Systemic delivery of sticky siRNAs targeting the cell cycle for lung tumor metastasis inhibition. Journal of Controlled Release : Official Journal of the Controlled Release Society. 170: 183-90
Perche P, Nothisen M, Bagilet J, et al. (2013) Cell-penetrating cationic siRNA and lipophilic derivatives efficient at nanomolar concentrations in the presence of serum and albumin Journal of Controlled Release. 170: 92-98
Paris C, Moreau V, Deglane G, et al. (2012) Conjugating phosphospermines to siRNAs for improved stability in serum, intracellular delivery and RNAi-mediated gene silencing. Molecular Pharmaceutics. 9: 3464-75
Liu X, Wu J, Yammine M, et al. (2011) Structurally flexible triethanolamine core PAMAM dendrimers are effective nanovectors for DNA transfection in vitro and in vivo to the mouse thymus. Bioconjugate Chemistry. 22: 2461-73
Schenk E, Essand M, Bangma CH, et al. (2010) Clinical adenoviral gene therapy for prostate cancer. Human Gene Therapy. 21: 807-13
de Vrij J, Willemsen RA, Lindholm L, et al. (2010) Adenovirus-derived vectors for prostate cancer gene therapy. Human Gene Therapy. 21: 795-805
Nothisen M, Kotera M, Voirin E, et al. (2009) Cationic siRNAs provide carrier-free gene silencing in animal cells. Journal of the American Chemical Society. 131: 17730-1
Moreau V, Voirin E, Paris C, et al. (2009) Zip Nucleic Acids: new high affinity oligonucleotides as potent primers for PCR and reverse transcription. Nucleic Acids Research. 37: e130
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