Jean-Paul Behr, Ph.D

Université Louis Pasteur, Strasbourg 
Chemistry, Nucleic acids, Transfection
"Jean-Paul Behr"
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Nothisen M, Perche-Létuvée P, Behr JP, et al. (2018) Cationic Oligospermine-Oligonucleotide Conjugates Provide Carrier-free Splice Switching in Monolayer Cells and Spheroids. Molecular Therapy. Nucleic Acids. 13: 483-492
Nothisen M, Bagilet J, Behr JP, et al. (2016) Structure Tuning of Cationic Oligospermine-siRNA Conjugates for Carrier-Free Gene Silencing. Molecular Pharmaceutics
Kedinger V, Meulle A, Zounib O, et al. (2013) Sticky siRNAs targeting survivin and cyclin B1 exert an antitumoral effect on melanoma subcutaneous xenografts and lung metastases. Bmc Cancer. 13: 338
Bonnet ME, Gossart JB, Benoit E, et al. (2013) Systemic delivery of sticky siRNAs targeting the cell cycle for lung tumor metastasis inhibition. Journal of Controlled Release : Official Journal of the Controlled Release Society. 170: 183-90
Perche P, Nothisen M, Bagilet J, et al. (2013) Cell-penetrating cationic siRNA and lipophilic derivatives efficient at nanomolar concentrations in the presence of serum and albumin Journal of Controlled Release. 170: 92-98
Paris C, Moreau V, Deglane G, et al. (2012) Conjugating phosphospermines to siRNAs for improved stability in serum, intracellular delivery and RNAi-mediated gene silencing. Molecular Pharmaceutics. 9: 3464-75
Yu T, Liu X, Bolcato-Bellemin AL, et al. (2012) An amphiphilic dendrimer for effective delivery of small interfering RNA and gene silencing in vitro and in vivo. Angewandte Chemie (International Ed. in English). 51: 8478-84
Behr JP. (2012) Synthetic gene transfer vectors II: back to the future. Accounts of Chemical Research. 45: 980-4
Liu X, Wu J, Yammine M, et al. (2011) Structurally flexible triethanolamine core PAMAM dendrimers are effective nanovectors for DNA transfection in vitro and in vivo to the mouse thymus. Bioconjugate Chemistry. 22: 2461-73
Schenk E, Essand M, Bangma CH, et al. (2010) Clinical adenoviral gene therapy for prostate cancer. Human Gene Therapy. 21: 807-13
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