Charles J Sih

Affiliations: 
Pharmacy University of Wisconsin, Madison, Madison, WI 
Area:
enzymatic catalyses to prepare enantiomerically-pure compounds; total synthesis of natural products; biosynthesis of vancomycin; and enzymatic mechanism of thyroxine biosynthesis
Website:
https://apps.pharmacy.wisc.edu/sopdir/charles_sih/
Google:
"Charles John Sih" OR "Charles J Sih"
Bio:

https://apps.pharmacy.wisc.edu/facstaff/sciences/pubs/Sih.pdf
https://books.google.com/books?id=nZQOAQAAMAAJ

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Parents

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Stanley G. Knight grad student 1958 UW Madison (Microtree)
 (The carbohydrate metabolism and cytochrome oxidase of Penicillium chrysogenum.)
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Publications

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Malnar I, Sih CJ. (2000) Synthesis of the bis-diaryl ether fragment of vancomycin via enzymatic oxidative phenolic coupling Tetrahedron Letters. 41: 1907-1911
Chen CA, Lu W, Sih CJ. (1999) Synthesis of 9Z, 11E-octadecadienoic and 10E, 12Z-octadecadienoic acids, the major components of conjugated linoleic acid Lipids. 34: 879-884
Zhang FJ, Gu QM, Sih CJ. (1999) Bioorganic chemistry of cyclic ADP-ribose (cADPR). Bioorganic & Medicinal Chemistry. 7: 653-64
Chen CA, Sih CJ. (1998) Chemoenzymatic synthesis of conjugated linoleic acid Journal of Organic Chemistry. 63: 9620-9621
Guo Z, Machiya K, Salamonczyk GM, et al. (1998) Total Synthesis of Bastadins 2, 3, and 6 The Journal of Organic Chemistry. 63: 4269-4276
Guo Z, Machiya K, Ma Y, et al. (1998) Enzymatic oxidative coupling of hydroxyphenylglycine derivatives Tetrahedron Letters. 39: 5679-5682
Salamonczyk GM, Han K, Guo Zw, et al. (1996) Total Synthesis of Cryptophycins via a Chemoenzymatic Approach. The Journal of Organic Chemistry. 61: 6893-6900
Schlosser M, Michel D, Guo Z, et al. (1996) α-Fluoro analogues of inflammation inhibiting α-arylpropionic acids Tetrahedron. 52: 8257-8262
Ditullio D, Anderson D, Chen CS, et al. (1994) L-carnitine via enzyme-catalyzed oxidative kinetic resolution. Bioorganic & Medicinal Chemistry. 2: 415-20
Gu Q, Sih CJ. (1994) Cyclic ADP-Ribose: Synthesis and Structural Assignment Journal of the American Chemical Society. 116: 7481-7486
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