Ke Ding, Ph.D

Affiliations: 
1991-1998 China Pharmaceutical University 
 1998-2001 Fudan university, Shanghai, Shanghai Shi, China 
 2006-2016 Guangzhou Institutes Biomedicine and Health,CAS 
 2016- Jinan University 
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"Ke Ding"
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Publications

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Yang J, Chang Y, Zhou K, et al. (2025) Discovery of : A Potent and Highly Selective Irreversible CDK12/13 Inhibitor with Synergistic Effects in Combination with Akt Inhibition. Journal of Medicinal Chemistry
Yang B, Xun Q, Tian Y, et al. (2025) Discovery of BW710 as a potent, selective and orally bioavailable fibroblast growth factor receptor 2 (FGFR2) inhibitor. European Journal of Medicinal Chemistry. 287: 117339
Li C, Chen Y, Huang W, et al. (2024) Structure-Based Design of "Head-to-Tail" Macrocyclic PROTACs. Jacs Au. 4: 4866-4882
Wen C, Gajjala PR, Liu Y, et al. (2024) Discovery of the first selective and potent PROTAC degrader for the pseudokinase TRIB2. European Journal of Medicinal Chemistry. 281: 117016
Zhou L, Zhou K, Chang Y, et al. (2024) Discovery of ZLC491 as a Potent, Selective, and Orally Bioavailable CDK12/13 PROTAC Degrader. Journal of Medicinal Chemistry
Zhang H, Lin G, Jia S, et al. (2024) Design, synthesis and evaluation of thieno[3,2-d]pyrimidine derivatives as novel potent CDK7 inhibitors. Bioorganic Chemistry. 148: 107456
Liu L, Zhao L, Yang L, et al. (2024) Discovery of as an Autophagy-Tethering Compound for the Degradation of Discoidin Domain Receptor 1. Journal of Medicinal Chemistry
Li H, Ke R, Zhou Y, et al. (2024) Discovery of LHQ490 as a highly selective fibroblast growth factor receptor 2 (FGFR2) inhibitor. European Journal of Medicinal Chemistry. 272: 116473
Liu L, Parolia A, Liu Y, et al. (2024) Discovery of LLC0424 as a Potent and Selective NSD2 PROTAC Degrader. Journal of Medicinal Chemistry
Niu P, Tao Y, Lin G, et al. (2024) Design and Synthesis of Novel Macrocyclic Derivatives as Potent and Selective Cyclin-Dependent Kinase 7 Inhibitors. Journal of Medicinal Chemistry
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