Ke Ding, Ph.D
Affiliations: | 1991-1998 | China Pharmaceutical University | |
| 1998-2001 | Fudan university, Shanghai, Shanghai Shi, China | ||
| 2006-2016 | Guangzhou Institutes Biomedicine and Health,CAS | ||
| 2016- | Jinan University |
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Sign in to add trainee| Fengtao Zhou | grad student | 2008-2013 | University of Chinese Academy of Sciences |
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Publications
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| Liu W, Bai Y, Zhou L, et al. (2023) Discovery of LWY713 as a potent and selective FLT3 PROTAC degrader with in vivo activity against acute myeloid leukemia. European Journal of Medicinal Chemistry. 264: 115974 |
| Zhang H, Lin G, Jia S, et al. (2023) Discovery and optimization of thieno[3,2-d]pyrimidine derivatives as highly selective inhibitors of cyclin-dependent kinase 7. European Journal of Medicinal Chemistry. 263: 115955 |
| Li C, Qiao Y, Jiang X, et al. (2023) Discovery of a First-in-Class Degrader for the Lipid Kinase PIKfyve. Journal of Medicinal Chemistry |
| Wei Y, Xu X, Jiang M, et al. (2023) Discovery of new Lenalidomide derivatives as potent and selective GSPT1 degraders. European Journal of Medicinal Chemistry. 258: 115580 |
| He R, Song Z, Bai Y, et al. (2023) Discovery of AXL Degraders with Improved Potencies in Triple-Negative Breast Cancer (TNBC) Cells. Journal of Medicinal Chemistry |
| Chan S, Zhang Y, Wang J, et al. (2022) Discovery of 3-Aminopyrazole Derivatives as New Potent and Orally Bioavailable AXL Inhibitors. Journal of Medicinal Chemistry |
| Zhang Y, Chan S, He R, et al. (2022) 1-Methyl-3-((4-(quinolin-4-yloxy)phenyl)amino)-1H-pyrazole-4-carboxamide derivatives as new rearranged during Transfection (RET) kinase inhibitors capable of suppressing resistant mutants in solvent-front regions. European Journal of Medicinal Chemistry. 244: 114862 |
| Li S, Zhang P, Xu F, et al. (2022) Ynamide Electrophile for the Profiling of Ligandable Carboxyl Residues in Live Cells and the Development of New Covalent Inhibitors. Journal of Medicinal Chemistry |
| Lu J, Huang Y, Huang J, et al. (2022) Discovery of the First Examples of Threonine Tyrosine Kinase PROTAC Degraders. Journal of Medicinal Chemistry |
| Zhang YH, Li YF, Wang Y, et al. (2020) Identification and characterization of N9-methyltransferase involved in converting caffeine into non-stimulatory theacrine in tea. Nature Communications. 11: 1473 |