Clifford D. Mol

Affiliations: 
Scripps Research Institute, La Jolla, La Jolla, CA, United States 
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"Clifford Mol"
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Tsutakawa SE, Shin DS, Mol CD, et al. (2013) Conserved structural chemistry for incision activity in structurally non-homologous apurinic/apyrimidinic endonuclease APE1 and endonuclease IV DNA repair enzymes. The Journal of Biological Chemistry. 288: 8445-55
Mol CD, Okada K, Hosfield DJ. (2009) Protein Kinase Structural Biology: Methods and Strategies for Targeted Drug Discovery Kinase Inhibitor Drugs. 485-500
Hosfield DJ, Mol CD. (2008) Targeting inactive kinases: Structure as foundation for cancer drug discovery Cancer Drug Design and Discovery. 229-252
Mol CD, Fabbro D, Hosfield DJ. (2004) Structural insights into the conformational selectivity of STI-571 and related kinase inhibitors. Current Opinion in Drug Discovery & Development. 7: 639-48
Mol CD, Dougan DR, Schneider TR, et al. (2004) Structural basis for the autoinhibition and STI-571 inhibition of c-Kit tyrosine kinase. The Journal of Biological Chemistry. 279: 31655-63
Mol CD, Brooun A, Dougan DR, et al. (2003) Crystal structures of active fully assembled substrate- and product-bound complexes of UDP-N-acetylmuramic acid:L-alanine ligase (MurC) from Haemophilus influenzae. Journal of Bacteriology. 185: 4152-62
Mol CD, Lim KB, Sridhar V, et al. (2003) Structure of a c-kit product complex reveals the basis for kinase transactivation. The Journal of Biological Chemistry. 278: 31461-4
Mol CD, Arvai AS, Begley TJ, et al. (2002) Structure and activity of a thermostable thymine-DNA glycosylase: evidence for base twisting to remove mismatched normal DNA bases. Journal of Molecular Biology. 315: 373-84
Hosfield DJ, Daniels DS, Mol CD, et al. (2001) DNA damage recognition and repair pathway coordination revealed by the structural biochemistry of DNA repair enzymes. Progress in Nucleic Acid Research and Molecular Biology. 68: 315-47
Mol CD, Hosfield DJ, Tainer JA. (2000) Abasic site recognition by two apurinic/apyrimidinic endonuclease families in DNA base excision repair: the 3' ends justify the means. Mutation Research. 460: 211-29
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