Mei-Jung Lai
Affiliations: | 2010 | College of Pharmacy | Taipei Medical University |
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Publications
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| Chou PY, Lai MJ, Tsai KK, et al. (2024) Syntheses of LSD1/HDAC Inhibitors with Demonstrated Efficacy against Colorectal Cancer: and Studies Including Patient-Derived Organoids. Journal of Medicinal Chemistry |
| Sethy B, Yu ZY, Narwanti I, et al. (2024) Design, synthesis, and biological evaluation of adenosine derivatives targeting DOT1L and HAT as anti-leukemia agents. Bioorganic Chemistry. 153: 107771 |
| Tang DW, Chen IC, Chou PY, et al. (2024) HSP90/LSD1 dual inhibitors against prostate cancer as well as patient-derived colorectal organoids. European Journal of Medicinal Chemistry. 278: 116801 |
| Sharma R, Chiang YH, Chen HC, et al. (2024) Dual inhibition of CYP17A1 and HDAC6 by abiraterone-installed hydroxamic acid overcomes temozolomide resistance in glioblastoma through inducing DNA damage and oxidative stress. Cancer Letters. 216666 |
| Sharma S, Wang SA, Yang WB, et al. (2024) First-in-Class Dual EZH2-HSP90 Inhibitor Eliciting Striking Antiglioblastoma Activity and . Journal of Medicinal Chemistry |
| Tsai FL, Huang HL, Lai MJ, et al. (2023) Anticancer Study of a Novel Pan-HDAC Inhibitor MPT0G236 in Colorectal Cancer Cells. International Journal of Molecular Sciences. 24 |
| Narwanti I, Yu ZY, Sethy B, et al. (2023) 6-Regioisomeric 5,8-quinolinediones as potent CDC25 inhibitors against colorectal cancers. European Journal of Medicinal Chemistry. 258: 115505 |
| Tseng HJ, Banerjee S, Qian B, et al. (2023) Design, synthesis, and biological activity of dual monoamine oxidase A and heat shock protein 90 inhibitors, N-Methylpropargylamine-conjugated 4-isopropylresorcinol for glioblastoma. European Journal of Medicinal Chemistry. 256: 115459 |
| Lai MJ, Lee HY, Chuang HY, et al. (2023) Correction to "-Sulfonyl-aminobiaryls as Antitubulin Agents and Inhibitors of Signal Transducers and Activators of Transcription 3 (STAT3) Signaling". Journal of Medicinal Chemistry |
| Nepali K, Wu AC, Lo WL, et al. (2023) Rationally designed donepezil-based hydroxamates modulate Sig-1R and HDAC isoforms to exert anti-glioblastoma effects. European Journal of Medicinal Chemistry. 248: 115054 |