David E. Thurston, PhD, FPharmS, GRIC, CChem
Affiliations: | 2012 | School of Pharmacy | University College London |
| 2012- | Institute of Pharmaceutical Science | King's College London, London, UK |
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Sign in to add trainee| K. Miraz Rahman | grad student | UCL | |
| Connie Chui | grad student | 2014- | King's College |
| Melina Hoffmann | grad student | 2016- | King's College |
| Ilona Pysz | grad student | 2016- | King's College |
| Paolo Andriollo | grad student | 2017- | King's College |
| Syafiq Kay | grad student | 2018- | King's College |
| Beatriz Padilla | grad student | 2012-2013 | King's College |
| Paul Jackson | grad student | 2012-2014 | King's College |
| Kaisar Islam | grad student | 2012-2016 | King's College |
| Julia Mantaj | grad student | 2012-2016 | King's College |
| Azadur Rahman | grad student | 2012-2016 | King's College |
| Sarah Zähringer | grad student | 2012-2016 | King's College |
| Christopher Chamberlain | grad student | 2012-2017 | King's College |
| Kamrun Nahar | grad student | 2012-2017 | King's College |
| Kazi Nahar | grad student | 2012-2017 | King's College |
| David Corcoran | grad student | 2013-2017 | King's College |
| Ranko Gacesa | grad student | 2013-2017 | King's College |
| Yong Xu | grad student | 2013-2018 | King's College |
| Geoffrey Wells | post-doc | 1998-2002 | University College London |
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Publications
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| Procopiou G, Jackson PJM, di Mascio D, et al. (2022) DNA sequence-selective G-A cross-linking ADC payloads for use in solid tumour therapies. Communications Biology. 5: 741 |
| Hoffmann RM, Mele S, Cheung A, et al. (2020) Rapid conjugation of antibodies to toxins to select candidates for the development of anticancer Antibody-Drug Conjugates (ADCs). Scientific Reports. 10: 8869 |
| Lewis T, Corcoran DB, Thurston DE, et al. (2020) Novel pyrrolobenzodiazepine benzofused hybrid molecules inhibit NF-κB activity and synergise with bortezomib and ibrutinib in hematological cancers. Haematologica |
| Pysz I, Jackson PJM, Barlow DJ, et al. (2020) UPLC-based assay to assess the hydrophobicity of Antibody-Drug Conjugate (ADC) payloads. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 1146: 122075 |
| Hoffmann RM, Crescioli S, Mele S, et al. (2020) A Novel Antibody-Drug Conjugate (ADC) Delivering a DNA Mono-Alkylating Payload to Chondroitin Sulfate Proteoglycan (CSPG4)-Expressing Melanoma. Cancers. 12 |
| Corcoran D, Lewis T, Nahar KS, et al. (2019) Effects of Systematic Shortening of Non-covalent C8-side Chain on the Cytotoxicity and NF-κB Inhibitory Capacity of Pyrrolobenzodiazepines. Journal of Medicinal Chemistry |
| Corcoran DB, Lewis T, Nahar KS, et al. (2019) Abstract 9: Effect of C8-side chain on the cytotoxicity and NF-kB inhibitory capacity of pyrrolobenzodiazepines Cancer Research. 79: 9-9 |
| Pysz I, Andriollo P, Jackson PJ, et al. (2019) Abstract 217: Development of a rapid and efficient methodology to quantitate thiol detection in antibody-drug conjugates (ADCs) Cancer Research. 79: 217-217 |
| Procopiou G, Auer J, Mascio Dd, et al. (2019) Abstract 211: A new class of sequence-selective DNA cross-linking ADC payloads with increasedin vivotolerability Cancer Research. 79: 211-211 |
| Veillard N, Andriollo P, Cascio F, et al. (2019) Abstract C030: A new low potency DNA guanine monoalkylating ADC payload with enhanced in vivo tolerability Molecular Cancer Therapeutics. 18 |