Shannon Marie Lauberth

University of California, San Diego, La Jolla, CA 
Epigenetics, p53 transcriptional regulation
"Shannon Lauberth"
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Morgan M, Shiekhattar R, Shilatifard A, et al. (2022) It's a DoG-eat-DoG world-altered transcriptional mechanisms drive downstream-of-gene (DoG) transcript production. Molecular Cell. 82: 1981-1991
Ohguchi H, Park PMC, Wang T, et al. (2021) Lysine Demethylase 5A is Required for MYC Driven Transcription in Multiple Myeloma. Blood Cancer Discovery. 2: 370-387
Sartorelli V, Lauberth SM. (2020) Enhancer RNAs are an important regulatory layer of the epigenome. Nature Structural & Molecular Biology. 27: 521-528
Rahnamoun H, Orozco P, Lauberth SM. (2019) The role of enhancer RNAs in epigenetic regulation of gene expression. Transcription. 1-7
Rahnamoun H, Lee J, Sun Z, et al. (2018) RNAs interact with BRD4 to promote enhanced chromatin engagement and transcription activation. Nature Structural & Molecular Biology. 25: 687-697
Rahnamoun H, Hong J, Sun Z, et al. (2018) Mutant p53 regulates enhancer-associated H3K4 monomethylation through interactions with the methyltransferase MLL4. The Journal of Biological Chemistry
Rahnamoun H, Lu H, Duttke SH, et al. (2017) Mutant p53 shapes the enhancer landscape of cancer cells in response to chronic immune signaling. Nature Communications. 8: 754
Stijf-Bultsma Y, Sommer L, Tauber M, et al. (2015) The basal transcription complex component TAF3 transduces changes in nuclear phosphoinositides into transcriptional output. Molecular Cell. 58: 453-67
Lauberth SM, Nakayama T, Wu X, et al. (2013) H3K4me3 interactions with TAF3 regulate preinitiation complex assembly and selective gene activation. Cell. 152: 1021-36
Lauberth SM, Bilyeu AC, Firulli BA, et al. (2007) A phosphomimetic mutation in the Sall1 repression motif disrupts recruitment of the nucleosome remodeling and deacetylase complex and repression of Gbx2. The Journal of Biological Chemistry. 282: 34858-68
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