Barry V. L. Potter, MA DPhil DSc FRSB FRSC MAE FMedSci

Affiliations: 
Max-Planck-Institute for Experimental Medicine, Göttingen, Germany 
 1984-1990 Biological Chemistry University of Leicester, Leicester, England, United Kingdom 
 1990- Medicine & Biological Chemistry University of Bath, Bath, England, United Kingdom 
 1998-2010 Sterix Ltd. 
 2015- Pharmacology University of Oxford, Oxford, United Kingdom 
Area:
medicinal chemistry, drug discovery, pharmacology
Website:
https://pharm.ox.ac.uk/research/potter-group-medicinal-biological-chemistry-drug-discovery
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"Barry Potter"
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Publications

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Nel M, Joubert AM, Dohle W, et al. (2018) Modes of cell death induced by tetrahydroisoquinoline-based analogs in MDA-MB-231 breast and A549 lung cancer cell lines. Drug Design, Development and Therapy. 12: 1881-1904
Fliegert R, Watt JM, Schöbel A, et al. (2017) Ligand induced activation of human TRPM2 requires the terminal ribose of ADPR and involves Arg 1433 and Tyr 1349. The Biochemical Journal
Thomas MP, Erneux C, Potter BV. (2016) SHIP2: Structure, Function and Inhibition. Chembiochem : a European Journal of Chemical Biology
Raimondi C, Calleja V, Ferro R, et al. (2016) A Small Molecule Inhibitor of PDK1/PLCγ1 Interaction Blocks Breast and Melanoma Cancer Cell Invasion. Scientific Reports. 6: 26142
El-Gamal MI, Semreen MH, Foster PA, et al. (2016) Design, synthesis, and biological evaluation of new arylamide derivatives possessing sulfonate or sulfamate moieties as steroid sulfatase enzyme inhibitors. Bioorganic & Medicinal Chemistry
Watson PJ, Millard CJ, Riley AM, et al. (2016) Insights into the activation mechanism of class I HDAC complexes by inositol phosphates. Nature Communications. 7: 11262
Mills SJ, Silvander C, Cozier GE, et al. (2016) Crystal Structures of Type-II Inositol Polyphosphate 5-Phosphatase INPP5B with Synthetic Inositol Polyphosphate Surrogates Reveal New Mechanistic Insights for the Inositol 5-Phosphatase Family. Biochemistry
Thomas MP, Mills SJ, Potter BV. (2015) The "Other" Inositols and Their Phosphates: Synthesis, Biology, and Medicine (with Recent Advances in myo-Inositol Chemistry). Angewandte Chemie (International Ed. in English)
Shen YC, Upadhyayula R, Cevallos S, et al. (2015) Targeted NF1 cancer therapeutics with multiple modes of action: small molecule hormone-like agents resembling the natural anticancer metabolite, 2-methoxyoestradiol. British Journal of Cancer. 113: 1158-67
Thomas MP, Potter BV. (2015) Estrogen O-sulfamates and their analogues: Clinical steroid sulfatase inhibitors with broad potential. The Journal of Steroid Biochemistry and Molecular Biology
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