Hideaki Nagase

Matrix Biology Kennedy institute of Rheumatology 
"Hideaki Nagase"
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Mohammed RN, Wehenkel SC, Galkina EV, et al. (2019) ADAM17-dependent proteolysis of L-selectin promotes early clonal expansion of cytotoxic T cells. Scientific Reports. 9: 5487
Solomonov I, Zehorai E, Talmi-Frank D, et al. (2016) Distinct biological events generated by ECM proteolysis by two homologous collagenases. Proceedings of the National Academy of Sciences of the United States of America
Doherty CM, Visse R, Dinakarpandian D, et al. (2016) Engineered Tissue Inhibitor of Metalloproteinases-3 Variants Resistant to Endocytosis Have Prolonged Chondroprotective Activity. The Journal of Biological Chemistry
Yamamoto K, Okano H, Miyagawa W, et al. (2016) MMP-13 is constitutively produced in human chondrocytes and co-endocytosed with ADAMTS-5 and TIMP-3 by the endocytic receptor LRP1. Matrix Biology : Journal of the International Society For Matrix Biology
Santamaria S, Yamamoto K, Botkjaer K, et al. (2015) Anti-body-based exosite inhibitors of ADAMTS-5 (Aggrecanase-2). The Biochemical Journal
Porazinski S, Wang H, Asaoka Y, et al. (2015) YAP is essential for tissue tension to ensure vertebrate 3D body shape. Nature. 521: 217-21
Ismail HM, Yamamoto K, Vincent TL, et al. (2015) Interleukin-1 Acts via the JNK-2 Signaling Pathway to Induce Aggrecan Degradation by Human Chondrocytes. Arthritis & Rheumatology (Hoboken, N.J.). 67: 1826-36
Lund J, Troeberg L, Kjeldal H, et al. (2015) Evidence for restricted reactivity of ADAMDEC1 with protein substrates and endogenous inhibitors. The Journal of Biological Chemistry. 290: 6620-9
Kelwick R, Wagstaff L, Decock J, et al. (2015) Metalloproteinase-dependent and -independent processes contribute to inhibition of breast cancer cell migration, angiogenesis and liver metastasis by a disintegrin and metalloproteinase with thrombospondin motifs-15. International Journal of Cancer. Journal International Du Cancer. 136: E14-26
Yamamoto K, Owen K, Parker AE, et al. (2014) Low density lipoprotein receptor-related protein 1 (LRP1)-mediated endocytic clearance of a disintegrin and metalloproteinase with thrombospondin motifs-4 (ADAMTS-4): functional differences of non-catalytic domains of ADAMTS-4 and ADAMTS-5 in LRP1 binding. The Journal of Biological Chemistry. 289: 6462-74
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