Sietske Bakker
Affiliations: | 2016 | University of California, San Francisco, San Francisco, CA |
Area:
Hematology, Cancer, DNA Repair, Stem Cells, Fanconi anemiaWebsite:
https://passeguelab.ucsf.edu/users/sietskeGoogle:
"Sietske Bakker"Bio:
https://research.vumc.nl/en/publications/fancm-the-mouse-that-roared
https://scholar.google.com/citations?user=Lz-wB-wAAAAJ&hl=en
Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Hein te Riele | grad student | 2011 | VU Amsterdam (GenetiTree) | |
| (FANCM, the mouse that roared) | ||||
| Emmanuelle Passegué | post-doc | 2016 | UCSF | |
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Publications
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| Mitchell CA, Verovskaya EV, Calero-Nieto FJ, et al. (2023) Stromal niche inflammation mediated by IL-1 signalling is a targetable driver of haematopoietic ageing. Nature Cell Biology |
| Ho TT, Dellorusso PV, Verovskaya EV, et al. (2021) Aged hematopoietic stem cells are refractory to bloodborne systemic rejuvenation interventions. The Journal of Experimental Medicine. 218 |
| Verovskaya E, Calero-Nieto F, Reynaud D, et al. (2018) Inflammatory Changes in the Bone Marrow Microenvironment Drive Both Niche and Blood System Remodeling during Aging Experimental Hematology. 64: S43-S44 |
| Verovskaya E, Reynaud D, Bakker S, et al. (2016) Remodeling of the multipotent progenitor (MPP) pool directly contributes to blood aging Experimental Hematology. 44: S54 |
| Flach J, Bakker ST, Mohrin M, et al. (2014) Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells. Nature. 512: 198-202 |
| Bakker ST, Passegué E. (2013) Resilient and resourceful: genome maintenance strategies in hematopoietic stem cells. Experimental Hematology. 41: 915-23 |
| Bakker ST, de Winter JP, te Riele H. (2013) Learning from a paradox: recent insights into Fanconi anaemia through studying mouse models. Disease Models & Mechanisms. 6: 40-7 |
| Bakker ST, van de Vrugt HJ, Visser JA, et al. (2012) Fancf-deficient mice are prone to develop ovarian tumours. The Journal of Pathology. 226: 28-39 |
| Flach J, Bakker S, Conroy P, et al. (2012) Increased γH2AX Foci in Old Hematopoietic Stem Cells Are Independent of the DNA Damage Response and Linked to Inefficient DNA Replication/Transcription Blood. 120: 1207-1207 |
| van de Vrugt HJ, Koomen M, Bakker S, et al. (2011) Evidence for complete epistasis of null mutations in murine Fanconi anemia genes Fanca and Fancg. Dna Repair. 10: 1252-61 |