Xin-Shan Ye, Ph.D.

Affiliations: 
2000- School of Pharmaceutical science Peking University Health Science Center, China 
Area:
Organic Chemistry; Medicinal Chemistry; Chemical Glycobiology
Website:
http://sklnbd.bjmu.edu.cn/k/e/action/ListInfo/?classid=14
Google:
"Xin-Shan Ye"
Bio:

EDUCATION
• B.Sc. Wuhan University, 1981-1985

• M. Sc. Wuhan University, 1985-1988 (supervised by Prof. Cheng-Tai Wu, Synthesis of crown ether compounds)

• Ph.D. The Chinese University of Hong Kong, 1993-1996 (supervised by Prof. Henry N. C. Wong, Synthesis of 3,4-disubstituted thiophenes)


ACADEMIC CAREER
• Lecturer Huazhong Agricultural University, 1988-1993

• Research Associate The Scripps Research Institute, USA, 1996-2000 (under the direction of Prof. Chi-Huey Wong, Synthesis of oligosaccharide library)

• Professor Peking University, 2000-


QUALIFICATIONS AND AWARDS
• Cheung Kong Scholars Programme Professionship (2000)

• National Outstanding Young Investigator Award by Natural Science Foundation of China (2005)

• Director of the State Key Laboratory of Natural and Biomimetic Drugs (2005-present)

• Natural Science Award of Ministry of Education, China, Second Class (2010)

• WuXi PharmaTech Life Science and Chemistry Award, Second Class (2010)

• Science and Technology Award of Chinese Pharmaceutical Association, First Class (2011)


RESEARCH INTERESTS
• Development of new methodologies or strategies for the assembly of oligosaccharides.

• Synthesis and evaluation of biologically important oligosaccharides such as tumor-associated antigens.

• Design, synthesis and evaluation of carbohydrate-processing enzyme inhibitors as well as discovery of new carbohydrate-based drugs.

• Chemical modifications of aminoglycoside antibiotics.


JOURNAL EDITING ACTIVITIES
• Co-Editors-in-Chief of Current Topics in Medicinal Chemistry (2014-)

• Member of International Advisory Board of ChemMedChem (2014-)

• Member of Editorial Board of Carbohydrate Research (2009-)

• Member of Editorial Board of Chinese Journal of Organic Chemistry (2007-)

• Member of Editorial Board of Chemical Journal of Chinese Universities (2007-)

• Member of Editorial Board of Chinese Journal of Medicinal Chemistry (2006-)

• Member of Editorial Board of Chinese Journal of New Drugs (2009-)

• Member of Editorial Board of Acta Scientiarum Naturalium Universitatis Pekinensis (2005-)

• Associate Editor-in-Chief of Journal of Chinese Pharmaceutical Sciences (2005-)
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Chen YF, Zhu JJ, Li J, et al. (2021) O-GlcNAcylation increases PYGL activity by promoting phosphorylation. Glycobiology
Chen YF, Shao GC, Li J, et al. (2021) O-GlcNAcylation of Blimp-1 in lymphocytes inhibits its transcriptional function and is associated with migration and invasion of breast cancer cells. Molecular Cancer Research : McR
Deng L, Song C, Niu Y, et al. (2021) Synthesis and biological evaluation of bergenin derivatives as new immunosuppressants. Rsc Medicinal Chemistry. 12: 1968-1976
Cao Y, Zhou M, Mao RZ, et al. (2021) Visible-light-promoted 3,5-dimethoxyphenyl glycoside activation and glycosylation. Chemical Communications (Cambridge, England). 57: 10899-10902
Li G, Ma W, Mo J, et al. (2021) Influenza Virus Precision Diagnosis and Continuous Purification Enabled by Neuraminidase-Resistant Glycopolymer-Coated Microbeads. Acs Applied Materials & Interfaces
Liu M, Qin X, Ye XS. (2021) Glycan Assembly Strategy: From Concept to Application. Chemical Record (New York, N.Y.)
Liu M, Luo ZX, Li T, et al. (2021) Electrochemical Trifluoromethylation of Glycals. The Journal of Organic Chemistry
Zhai C, Zheng XJ, Song C, et al. (2021) Synthesis and immunological evaluation of -acyl modified Globo H derivatives as anticancer vaccine candidates. Rsc Medicinal Chemistry. 12: 1239-1243
Wu X, Wu Y, Zheng R, et al. (2021) Sensing of mycobacterial arabinogalactan by galectin-9 exacerbates mycobacterial infection. Embo Reports. e51678
Zhang ZP, Xue WY, Hu JX, et al. (2020) Novel carbohydrate-triazole derivatives as potential α-glucosidase inhibitors. Chinese Journal of Natural Medicines. 18: 729-737
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