James S. Fraser

Affiliations: 
University of California, San Francisco, San Francisco, CA 
Area:
Structural Biology
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"James Fraser"
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Publications

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Riley BT, Wankowicz SA, de Oliveira SHP, et al. (2020) qFit 3: Protein and ligand multiconformer modeling for X-ray crystallographic and single-particle cryo-EM density maps. Protein Science : a Publication of the Protein Society
Wolff AM, Young ID, Sierra RG, et al. (2020) Comparing serial X-ray crystallography and microcrystal electron diffraction (MicroED) as methods for routine structure determination from small macromolecular crystals. Iucrj. 7: 306-323
Dasgupta M, Budday D, de Oliveira SHP, et al. (2019) Mix-and-inject XFEL crystallography reveals gated conformational dynamics during enzyme catalysis. Proceedings of the National Academy of Sciences of the United States of America
van Zundert G, Hudson BM, de Oliveira S, et al. (2018) qFit-ligand reveals widespread conformational heterogeneity of drug-like molecules in X-ray electron density maps. Journal of Medicinal Chemistry
Keedy DA, Hill ZB, Biel JT, et al. (2018) An expanded allosteric network in PTP1B by multitemperature crystallography, fragment screening, and covalent tethering. Elife. 7
Russi S, González A, Kenner LR, et al. (2017) Conformational variation of proteins at room temperature is not dominated by radiation damage. Journal of Synchrotron Radiation. 24: 73-82
Mavor D, Barlow K, Thompson S, et al. (2016) Determination of ubiquitin fitness landscapes under different chemical stresses in a classroom setting. Elife. 5
Meyer PA, Socias S, Key J, et al. (2016) Data publication with the structural biology data grid supports live analysis. Nature Communications. 7: 10882
Cimermancic P, Weinkam P, Rettenmaier TJ, et al. (2016) CryptoSite: Expanding the Druggable Proteome by Characterization and Prediction of Cryptic Binding Sites. Journal of Molecular Biology
Keedy DA, Fraser JS, van den Bedem H. (2015) Exposing Hidden Alternative Backbone Conformations in X-ray Crystallography Using qFit. Plos Computational Biology. 11: e1004507
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