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Roy Parker

Chemistry and Biochemistry University of Colorado, Boulder, Boulder, CO, United States 
Control of mRNA Function in Eukaryotic Cells
"Roy Parker"

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Christine Guthrie grad student 1985 UCSF
 (A genetic analysis of mRNA splicing in S̲a̲c̲c̲h̲a̲r̲o̲m̲y̲c̲e̲s̲ c̲e̲r̲e̲v̲i̲s̲i̲a̲e̲)
Allan Jacobson post-doc (Neurotree)
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Shehata SI, Watkins JM, Burke JM, et al. (2024) Mechanisms and consequences of mRNA destabilization during viral infections. Virology Journal. 21: 38
Ripin N, Parker R. (2023) Formation, function, and pathology of RNP granules. Cell. 186: 4737-4756
Huynh TN, Parker R. (2023) The PARN, TOE1, and USB1 RNA deadenylases and their roles in non-coding RNA regulation. The Journal of Biological Chemistry. 299: 105139
Shehata SI, Parker R. (2023) SARS-CoV-2 Nsp1 mediated mRNA degradation requires mRNA interaction with the ribosome. Rna Biology. 20: 444-456
Burke JM, Ripin N, Ferretti MB, et al. (2022) RNase L activation in the cytoplasm induces aberrant processing of mRNAs in the nucleus. Plos Pathogens. 18: e1010930
Khong A, Matheny T, Huynh TN, et al. (2022) Limited effects of mA modification on mRNA partitioning into stress granules. Nature Communications. 13: 3735
Decker CJ, Burke JM, Mulvaney PK, et al. (2022) RNA is required for the integrity of multiple nuclear and cytoplasmic membrane-less RNP granules. The Embo Journal. e110137
Corbet GA, Burke JM, Parker R. (2021) ADAR1 limits stress granule formation through both translation-dependent and translation-independent mechanisms. Journal of Cell Science
Burke JM, St Clair LA, Perera R, et al. (2021) SARS-CoV-2 infection triggers widespread host mRNA decay leading to an mRNA export block. Rna (New York, N.Y.)
Burke JM, Gilchrist AR, Sawyer SL, et al. (2021) RNase L limits host and viral protein synthesis via inhibition of mRNA export. Science Advances. 7
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