Ivan Ahel

Affiliations: 
Oxford University UK 
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"Ivan Ahel"
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Hewitt G, Borel V, Segura-Bayona S, et al. (2020) Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD. Molecular Cell
Lawarée E, Jankevicius G, Cooper C, et al. (2020) DNA ADP-Ribosylation Stalls Replication and Is Reversed by RecF-Mediated Homologous Recombination and Nucleotide Excision Repair. Cell Reports. 30: 1373-1384.e4
Posavec Marjanovic M, Jankevicius G, Ahel I. (2018) Hydrolysis of ADP-Ribosylation by Macrodomains. Methods in Molecular Biology (Clifton, N.J.). 1813: 215-223
Fehr AR, Jankevicius G, Ahel I, et al. (2017) Viral Macrodomains: Unique Mediators of Viral Replication and Pathogenesis. Trends in Microbiology
Marjanović MP, Hurtado-Bagès S, Lassi M, et al. (2017) MacroH2A1.1 regulates mitochondrial respiration by limiting nuclear NAD(+) consumption. Nature Structural & Molecular Biology
Fehr AR, Channappanavar R, Jankevicius G, et al. (2016) The Conserved Coronavirus Macrodomain Promotes Virulence and Suppresses the Innate Immune Response during Severe Acute Respiratory Syndrome Coronavirus Infection. Mbio. 7
Jankevicius G, Ariza A, Ahel M, et al. (2016) The Toxin-Antitoxin System DarTG Catalyzes Reversible ADP-Ribosylation of DNA. Molecular Cell. 64: 1109-1116
Lalić J, Posavec Marjanović M, Palazzo L, et al. (2016) Disruption of macrodomain protein SCO6735 increases antibiotic production in Streptomyces coelicolor. The Journal of Biological Chemistry
Li C, Debing Y, Jankevicius G, et al. (2016) Viral Macro Domains Reverse Protein ADP-ribosylation. Journal of Virology
Rack JG, Morra R, Barkauskaite E, et al. (2015) Identification of a Class of Protein ADP-Ribosylating Sirtuins in Microbial Pathogens. Molecular Cell. 59: 309-20
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