Fred D. Ledley, M.D.

1983-1995 Cell Biology Baylor College of Medicine, Houston, TX 
 2005- Natural & Applied Science, Management, Center for Integration of Science and Industry Bentley University 
genetic medicine, personalized medicine, biotechnology, drug development, management
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Leonard D. Kohn grad student 1975-1978 NIH
Savio L.C. Woo post-doc 1984- Baylor College of Medicine (Cell & Gene Therapy Tree)
David Baltimore post-doc 1981-1983 MIT
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Ledley FD, McNamee LM, Uzdil V, et al. (2014) Why commercialization of gene therapy stalled; examining the life cycles of gene therapy technologies. Gene Therapy. 21: 188-94
Rosenberg SA, Blaese RM, Brenner MK, et al. (2000) Human gene marker/therapy clinical protocols. Human Gene Therapy. 11: 919-79
Shapiro Ledley T, Ledley FD. (1998) Pharmacokinetic considerations in somatic gene therapy. Advanced Drug Delivery Reviews. 30: 133-150
Ledley FD, Rosenblatt DS. (1997) Mutations in mut methylmalonic acidemia: clinical and enzymatic correlations. Human Mutation. 9: 1-6
Ledley FD. (1996) Pharmaceutical approach to somatic gene therapy. Pharmaceutical Research. 13: 1595-614
Adams RM, Wang M, Crane AM, et al. (1995) Effective cryopreservation and long-term storage of primary human hepatocytes with recovery of viability, differentiation, and replicative potential. Cell Transplantation. 4: 579-86
Lau C, Soriano HE, Ledley FD, et al. (1995) Retroviral gene transfer into the intestinal epithelium. Human Gene Therapy. 6: 1145-51
Ledley FD. (1995) Nonviral gene therapy: the promise of genes as pharmaceutical products. Human Gene Therapy. 6: 1129-44
Ledley FD. (1995) After gene therapy: issues in long-term clinical follow-up and care. Advances in Genetics. 32: 1-16
Yovandich J, O'Malley B, Sikes M, et al. (1995) Gene transfer to synovial cells by intra-articular administration of plasmid DNA Human Gene Therapy. 6: 603-610
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