Salih J. Wakil
Affiliations: | Biochemistry and Molecular Biology | Baylor College of Medicine, Houston, TX |
Area:
fatty acid metabolism and the metabolic syndromeWebsite:
https://www.bcm.edu/departments/biochemistry-and-molecular-biology/?PMID=3794Google:
"Salih Jawad al-Wakil"Bio:
http://www.nasonline.org/member-directory/members/1634.html
Mean distance: 9.63 | S | N | B | C | P |
Parents
Sign in to add mentor| Donald J. Hanahan | grad student | 1952 | University of Washington | |
| (Biosynthesis of labeled ergosterol from isotopic acetate. The origin of some of the carbon atoms of the side chain of ergosterol. Metabolism of C¹⁴-ergosterol) | ||||
| David E. Green | post-doc | UW Madison | ||
Children
Sign in to add trainee| Eugene M Barnes | grad student | 1970 | Duke |
| Zendra Elizabeth Zehner | grad student | 1979 | Baylor College of Medicine |
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Publications
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| Jung D, Abu-Elheiga L, Ayuzawa R, et al. (2012) Mislocalization and inhibition of acetyl-CoA carboxylase 1 by a synthetic small molecule. The Biochemical Journal. 448: 409-16 |
| Abu-Elheiga L, Wu H, Gu Z, et al. (2012) Acetyl-CoA carboxylase 2-/- mutant mice are protected against fatty liver under high-fat, high-carbohydrate dietary and de novo lipogenic conditions. The Journal of Biological Chemistry. 287: 12578-88 |
| Zhang W, Chakravarty B, Zheng F, et al. (2011) Crystal structure of FAS thioesterase domain with polyunsaturated fatty acyl adduct and inhibition by dihomo-gamma-linolenic acid. Proceedings of the National Academy of Sciences of the United States of America. 108: 15757-62 |
| Mao J, Yang T, Gu Z, et al. (2009) aP2-Cre-mediated inactivation of acetyl-CoA carboxylase 1 causes growth retardation and reduced lipid accumulation in adipose tissues. Proceedings of the National Academy of Sciences of the United States of America. 106: 17576-81 |
| Kamisuki S, Mao Q, Abu-Elheiga L, et al. (2009) A small molecule that blocks fat synthesis by inhibiting the activation of SREBP. Chemistry & Biology. 16: 882-92 |
| Wakil SJ, Abu-Elheiga LA. (2009) Fatty acid metabolism: target for metabolic syndrome. Journal of Lipid Research. 50: S138-43 |
| Mao J, DeMayo FJ, Li H, et al. (2006) Liver-specific deletion of acetyl-CoA carboxylase 1 reduces hepatic triglyceride accumulation without affecting glucose homeostasis. Proceedings of the National Academy of Sciences of the United States of America. 103: 8552-7 |
| Abu-Elheiga L, Matzuk MM, Kordari P, et al. (2005) Mutant mice lacking acetyl-CoA carboxylase 1 are embryonically lethal. Proceedings of the National Academy of Sciences of the United States of America. 102: 12011-6 |
| Oh W, Abu-Elheiga L, Kordari P, et al. (2005) Glucose and fat metabolism in adipose tissue of acetyl-CoA carboxylase 2 knockout mice. Proceedings of the National Academy of Sciences of the United States of America. 102: 1384-9 |
| Chirala SS, Wakil SJ. (2004) Structure and function of animal fatty acid synthase. Lipids. 39: 1045-53 |